Results 121 to 130 of about 140,911 (217)

SIMVASTATIN as a potential protective strategy against doxorubicin-induced cardiotoxicity. [PDF]

Front Cardiovasc Med
Pala B, Piscione M, Di Marcantonio MC, Cribari F, Vitale R, Baldi T, Popolo A, Mincione G.   +7 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

From prediction to intervention: Paradigm shifts in causal AI for precision medicine and large‐scale cohorts

VIEW, EarlyView.
Large‐scale cohorts and multimodal biomedical data have enabled powerful predictive models for clinical risk stratification, but prediction alone cannot guide effective interventions. This review introduces causal artificial intelligence as a design‐first framework that integrates target trial emulation, causal discovery, and robust effect estimation ...
Linlin Cao, Yudian Xu, Yifan Chen, Honghao Huang, Wei Xu, Jun Pu   +5 more
wiley   +1 more source

Isolated Gamma-Glutamyltransferase Elevation During Statin Therapy: A Diagnostic Pitfall and a Stepwise Management Framework to Prevent Unnecessary Discontinuation. [PDF]

Clin Case Rep
Yang J, He Y, Zhang Z.
europepmc   +1 more source

Adverse events associated with statin co-use in breast cancer patients: a disproportionality analysis based on the FDA Adverse Event Reporting System. [PDF]

Ther Adv Drug Saf
Zhang Y, Peng W, Yang W, Gao Y, Fan Y, Guo Q.   +5 more
europepmc   +1 more source

What Causes Geographic Variation in Drug Prescribing? Evidence from Physician Migration

The RAND Journal of Economics, EarlyView.
ABSTRACT In this article, we examine the importance of individual physicians in explaining the significant variation in prescription drug spending in Medicare Part D. By tracking prescribing behavior before and after physician relocations, we find that movers' prescribing converges toward the average of their new location.
David Beheshti, Seth Neller
wiley   +1 more source

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021-2025 State-of-the-Art Review of Clinical and Preclinical Evidence. [PDF]

Pharmacol Res Perspect
Chiatto LM, Buccarello L, Carota G, Calabrò RS, Rifici C, Esposito E, Ardizzone A, Caruso G.   +7 more
europepmc   +1 more source

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

ROS-responsive nanocarriers for the delivery of atorvastatin in ischemic MCAO rats promoting neuroprotection. [PDF]

Mater Today Bio
Nagareddy R, Sundaram A, Kim JH, Kim JH, Vasvani S, Kweon S, Park IK, Jeong YY, Choi KH.   +8 more
europepmc   +1 more source

Timely Delivery of Care and the Optimal Care Pathway for People With Colorectal Cancer: A Scoping Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
The “Optimal care pathway for people with colorectal cancer” is a framework designed to support clinicians delivering high‐quality, timely care to patients; however, it is unknown whether this has affected outcomes across Australia. The variable results in this review suggest that this guideline is yet to be integrated nationally. ABSTRACT The “Optimal
Elliott Benjamin Fox, Dennis Perez Castillo, Nathan Bain, Amy Brown   +3 more
wiley   +1 more source