Results 221 to 230 of about 227,662 (304)

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Statin use and oncologic outcomes following neoadjuvant therapy for esophageal cancer. [PDF]

J Thorac Dis
van der Aa DC, Anderegg MCJ, Bergman JJGHM, Meijer SL, Lagarde SM, van Berge Henegouwen MI, van Laarhoven HWM, Gisbertz SS.   +7 more
europepmc   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

Association between statin therapy as primary prevention and mortality in adults 50 years and older with chronic kidney disease without other indications. [PDF]

Scand J Prim Health Care
Malmquist J, Davidge J, Bjurström K, Halling A, Agvall B.   +4 more
europepmc   +1 more source

Effect of Early Radiographic Bone Loss Before Loading on Implant‐Related Outcomes: A Long‐Term Retrospective Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This retrospective study primarily evaluated whether early radiographic bone loss (ERBL) predicts progressive bone loss (PBL), and secondarily assessed its association with implant survival and peri‐implant diseases. Methods Adults with dental implants who were followed for at least 5 years were included.
Dominick Moser, Engin Ozgur, Jennifer Tjokro, Clemens Raabe, Vivianne Chappuis, Gustavo Avila‐Ortiz, Pablo Galindo‐Moreno, Miguel Padial‐Molina, Emilio Couso‐Queiruga   +8 more
wiley   +1 more source

Anti-Tumor Effects of Statins in Pancreatic Ductal Adenocarcinoma Cells. [PDF]

Int J Mol Sci
Kucháriková V, Hatoková Z, Baranovičová E, Baďurová B, Pavlišová T, Kotúľová L, Kalman M, Marcinek J, Chodelková O, Nováková S, Strnádel J, Škovierová H, Halašová E.   +12 more
europepmc   +1 more source

Long‐term disease control of disseminated superficial actinic porokeratosis (DSAP) with simvastatin 2%/ cholesterol 2% cream

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Introduction Disseminated superficial actinic porokeratosis (DSAP) is a rare keratinization disorder associated with an increased risk of cutaneous tumors. Objectives To develop a feasible and easy‐to‐apply treatment regimen for long‐time disease control of DSAP including prevention of new skin tumors. Patients and Methods 19 patients with DSAP
Berenice M. Lang, Gregor Ojak, Mandy Crummenauer, Joanna Wegner, Caroline Mann, Stephan Grabbe, Petra Staubach   +6 more
wiley   +1 more source

Risk of progression to type 2 diabetes or regression to normoglycaemia among Ghanaians with prediabetes living in Ghana and the Netherlands: The RODAM prospective study

Diabetic Medicine, EarlyView.
Abstract Introduction Evidence shows that ethnicity affects the risk of progression of prediabetes to type 2 diabetes(T2D) or regression to normoglycaemia However, little is known about progression rates among sub‐Saharan African populations or whether geographical context affects risk variations.
Emmanuel Bannerman‐Williams, Yacoba Atiase, Bert‐Jan H. van den Born, Felix Patience Chilunga, Eva van der Linden, Karlijn A. C. Meeks, Erik Beune, Charles Agyemang, Charles Frederick Hayfron‐Benjamin   +8 more
wiley   +1 more source

Effect of renin-angiotensin-aldosterone system inhibitor and statin medication on periodontal status of patients at risk of cardiovascular disease: a systematic review and meta-analysis. [PDF]

Saudi Dent J
Khalilurrahman ZA, Anjani SK, Sulijaya B, Haerani N, Lessang R, Harsas NA, Rahdewati H.   +6 more
europepmc   +1 more source

The burden of diabetic foot ulcers in a multi‐ethnic Asian cohort

Diabetic Medicine, EarlyView.
Abstract Aims Diabetic foot ulcers (DFUs) are a major source of morbidity among individuals with diabetes mellitus (DM), imposing a substantial burden on healthcare systems. Our institution established a multidisciplinary service aiming to facilitate early specialist intervention for DFU management.
Zongwen Wee, Yong Mong Bee, Sueziani Binte Zainudin   +2 more
wiley   +1 more source