Results 71 to 80 of about 223,681 (205)

Effect of Statins in Patients With Hemodialysis‐Dependent Chronic Kidney Disease: A Nationwide Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Guidelines for lipid‐lowering therapy in patients with dialysis‐dependent chronic kidney disease remain ambiguous. We aimed to explore cardiovascular outcomes associated with statin use in patients with hemodialysis‐dependent chronic kidney ...
Minyoul Baik, Jimin Jeon, Joonsang Yoo, Jinkwon Kim   +3 more
doaj   +1 more source

Therapeutic inertia in statin therapy for secondary prevention after percutaneous coronary intervention: a nationwide population-based cohort study

BMC Cardiovascular Disorders
Background Therapeutic inertia is defined as the failure to provide guideline-directed therapy and is a barrier to achieving optimal clinical outcomes.
Young-Hoon Seo, Jee-Young Hong, Yong-Kyun Kim, Ki-Hong Kim, Taek-Geun Kwon, Jang-Ho Bae   +5 more
doaj   +1 more source

Statins and Risk of Intracerebral Haemorrhage in a Stroke-Free Population: A Nationwide Danish Propensity Score Matched Cohort Study

EClinicalMedicine, 2019
Background: Statins may increase the risk of intracerebral haemorrhage (ICH) in individuals with previous stroke. It remains unclear whether this applies to individuals with no history of stroke.
Anette Riisgaard Ribe, Claus Høstrup Vestergaard, Mogens Vestergaard, Morten Fenger-Grøn, Henrik Schou Pedersen, Lone Winther Lietzen, Peter Krogh Brynningsen   +6 more
doaj   +1 more source

Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]

, 2018
Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J, Budoff, Matthew, Le, Viet T, May, Heidi T, Nelson, John R, Roy, Sion   +5 more
core   +2 more sources

Intensive versus standard dose statin therapy: the costs and benefits for patients with acute coronary syndrome [PDF]

Introduction: Recent NICE guidance in England and Wales states that statin therapy for secondary CVD should "usually be initiated with a drug with a low acquisition cost (taking into account required daily dose and product price per dose)".
Ara, R., Hall, A.S., Pandor, A., Ward, S.   +3 more
core   +3 more sources

Statin adherence is lower in primary than secondary prevention: A national follow-up study of new users.

PLoS ONE, 2020
BackgroundMaintaining adherence to statins reduces the risk of an initial cardiovascular disease (CVD) event in high-risk individuals (primary prevention) and additional CVD events following the first event (secondary prevention).
Finn Sigglekow, Simon Horsburgh, Lianne Parkin   +2 more
doaj   +1 more source

Statin use and survival in resectable pancreatic cancer: confounders and mechanisms. [PDF]

, 2016
A first point regards the possible activity of drugs other than statins, such as aspirin or metformin, against pancreatic cancer. As many patients use a combination of these drugs, one might speculate that the association between simvastatin and overall ...
Archibugi, L, Capurso, G, DELLE FAVE, Gianfranco   +2 more
core   +1 more source

Effects of statins on the development of sepsis and organ dysfunction in hospitalized older patients in China

Brazilian Journal of Infectious Diseases, 2017
This study aimed to evaluate the protective role of statins on the development of sepsis and infection-related organ dysfunction and mortality in a hospitalized older Chinese population with bacterial infections.
Qifeng Gui, Yunmei Yang, Jiajia Zhang
doaj   +1 more source

"STATINS KALEIDOSCOPE". MYOPATHY FROM STATINS

, 2019
Statins are medications that inhibit the 3-hydroxy-3-methylglutaryl-CoA reductase enzyme, thus inhibiting cholesterol biosynthesis. Statins reduce cardiovascular risk and morbidity in patients with coronaropathia, however, without forgetting their side effect in muscle toxicity. Clinically, patients with myopathy caused by statins are divided into four
ERVIN RAPUSHI, TEUTA BRACKA, ARTUR ZOTO, LEDIANA NUHAJ, INDIN XHEMALI   +4 more
openaire   +1 more source

Risk Factors for Long-Term Coronary Artery Calcium Progression in the Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2015
BackgroundCoronary artery calcium (CAC) detected by noncontrast cardiac computed tomography scanning is a measure of coronary atherosclerosis burden. Increasing CAC levels have been strongly associated with increased coronary events.
Blaha, Michael J, Budoff, Matthew, Gassett, Amanda J, Kaufman, Joel D, Kronmal, Richard, McClelland, Robyn L, Olives, Casey, Sheppard, Lianne   +7 more
core   +2 more sources