Results 161 to 170 of about 150,085 (313)

Statins : understanding clinical use /

open access: yes, 2004
Includes bibliographical references and index.Print version record ...
Mehta, Jawahar.
core  

Asymptomatic Cardiotoxicity After High‐Dose Anthracycline Treatment in Sarcoma Patients Assessed by Biomarkers and Echocardiography

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski   +6 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Is a statin a statin?

open access: yesInternational Journal of Clinical Practice, 2001
openaire   +2 more sources

Study on Regulation of Osteoblastic Differentiation by an Inhibitor of Cholesterol Synthesis (Statin).

open access: yes, 2004
P(論文)The cholesterol-lowering drugs statins, including simvastatin, cerivastatin and atorvastatin, are pro-drug of a potent 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors and inhibit cholesterol synthesis in humans and animals ...
マエダ, トヨノブ   +5 more
core  

TRIM31–LOX‐1 Axis: A Novel Therapeutic Frontier in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis, driven by a vicious cycle of lipid accumulation and chronic inflammation, underlies most cardiovascular diseases. Macrophages exacerbate this process by internalizing oxidized low‐density lipoprotein (oxLDL), forming foam cells, and releasing inflammatory mediators. A recent study published in Circulation identified the TRIM31–
Qian Zhang, Cheng Xue Qin
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Pleiotropic vasoprotective effects of statins: The chicken or the egg?

open access: yes, 2009
Dimitrios Kirmizis, Dimitrios ChatzidimitriouAristotle University, Thessaloniki, GreeceAbstract: Statins (3-hydroxy-3-methyl glutaryl coenzyme A [HMG-CoA] reductase inhibitors) are the most commonly used lipid-lowering drugs.
Dimitrios Kirmizis   +1 more
core  

Association Between Preoperative Dyslipidemia and the Prognosis of Patients With Endometrial Cancer: A Retrospective Cohort Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Endometrial cancer (EC) is closely related to metabolic disorders. We aimed to investigate whether preoperative dyslipidemia independently affects the prognosis of patients with EC. One hundred and ninety‐four women diagnosed with EC by pathology and who had undergone standardized surgical treatment at the Affiliated Hospital of Jining Medical
Song Li   +5 more
wiley   +1 more source

Optimal Timing of Statin Initiation for Patients with Type 2 Diabetes

open access: yes, 2009
HMG Co-A reductase inhibitors (statins) are an important part of the treatment plan for patients with type 2 diabetes. However, the optimal time to initiate treatment is influenced by many factors. We investigate two such factors in this thesis: (1) the
Mason, Jennifer Elizabeth
core  

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