Results 161 to 170 of about 124,347 (217)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia +6 more
wiley +1 more source
A comprehensive review of cancer‐induced cardiac wasting
British Journal of Pharmacology, EarlyView.Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena +5 more
wiley +1 more source
Lipid lowering in coronary artery disease - not just statins. [PDF]
Clin Med (Lond)Han J, Masmanian E, Wang T, Chua TP.
europepmc +1 more source
Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes +7 more
wiley +1 more source
The effect of statins on the survival of patients with amyotrophic lateral sclerosis: a meta-analysis. [PDF]
Front NeurolZhou H, Meng T, Liang D, Wang Y.
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder +7 more
wiley +1 more source
SIMVASTATIN as a potential protective strategy against doxorubicin-induced cardiotoxicity. [PDF]
Front Cardiovasc MedPala B +7 more
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam +4 more
wiley +1 more source
Non-adherence to Statin Treatment: A Narrative Review of Causes, Clinical Impact, and Preventive Strategies. [PDF]
CureusMróz T, Morka J, Sobczak M, Morajko A.
europepmc +1 more source
Effect of Medication Intake on Dental Implant‐Related Outcomes—A Scoping Review
Clinical Oral Implants Research, EarlyView.ABSTRACT Objective The objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients. Material and Methods Electronic and manual searches were conducted for this scoping review.
Alberto Monje +4 more
wiley +1 more source