Patient‐Reported Reasons for Declining or Discontinuing Statin Therapy: Insights From the PALM Registry [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Many adults eligible for statin therapy for cardiovascular disease prevention are untreated. Our objective was to investigate patient‐reported reasons for statin underutilization, including noninitiation, refusal, and discontinuation.
Corey K. Bradley +10 more
doaj +3 more sources
The relationship between statin therapy and adipocytokine/inflammatory mediators in dyslipidemic nondiabetic patients: A comparative study [PDF]
Pharmacia, 2023 Background: Statins have emerged as a vital therapeutic option for dyslipidemia, effectively reducing morbidity and mortality in individuals with various medical conditions.
Hany A. Al-hussaniy +3 more
doaj +3 more sources
A multistate transition model for statin‐induced myopathy and statin discontinuation
CPT: Pharmacometrics & Systems Pharmacology, 2021 The overarching goal of this study was to simultaneously model the dynamic relationships among statin exposure, statin discontinuation, and potentially statin‐related myopathic outcomes.
Yuxi Zhu +9 more
doaj +1 more source
Statin use and cognitive function: population-based observational study with long-term follow-up. [PDF]
PLoS ONE, 2015 We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0-10;
Hanneke Joosten +6 more
doaj +1 more source
Impact of metformin on statin‐associated myopathy risks in dyslipidemia patients
Pharmacology Research & Perspectives, 2023 A growing number of patients with metabolic disorders are receiving statin and antidiabetic therapies as comedications. A signal of increased risk of myotoxicity due to potential interactions between antidiabetics and statins has been detected in ...
Keunhyeong Bak +4 more
doaj +1 more source
Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort
Cardiovascular Diabetology, 2022 Background Prior studies of the glycemic effect of statins have been inconsistent. Also, most studies have only considered a short duration of statin use; the effect of long-term statin use on fasting glucose (FG) has not been well examined.
Tanushree Haldar +7 more
doaj +1 more source
Effect of statins on venous thromboembolic events: a meta-analysis of published and unpublished evidence from randomised controlled trials [PDF]
, 2012 Background - It has been suggested that statins substantially reduce the risk of venous thromboembolic events. We sought to test this hypothesis by performing a meta-analysis of both published and unpublished results from randomised trials of statins.
, +10 more
core +12 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Whether statin use can reduce the risk of heart failure (HF) remains controversial. The present study evaluates the association between statin use and HF in patients with atrial fibrillation.
Jia‐Yi Huang +15 more
doaj +1 more source
Statin Use and Risk of Prostate Cancer : A Meta-Analysis of Observational Studies [PDF]
, 2012 Background: Emerging evidence suggests that statins may decrease the risk of cancers. However, available evidence on prostate cancer (PCa) is conflicting.
Dipika Bansal +4 more
core +11 more sources
Statin use after acute myocardial infarction by patient complexity: Are the rates right? [PDF]
, 2015 Reprinted with permission of the publisher.Background: Guidelines suggest statin use after acute myocardial infarction (AMI) should be close to universal in patients without safety concerns yet rates are much lower than recommended, decline with patient ...
Abd +36 more
core +1 more source