Results 1 to 10 of about 140,911 (217)

Patient‐Reported Reasons for Declining or Discontinuing Statin Therapy: Insights From the PALM Registry

open access: yesJournal of the American Heart Association, 2019
Background Many adults eligible for statin therapy for cardiovascular disease prevention are untreated. Our objective was to investigate patient‐reported reasons for statin underutilization, including noninitiation, refusal, and discontinuation.
Corey K Bradley   +2 more
exaly   +3 more sources

The relationship between statin therapy and adipocytokine/inflammatory mediators in dyslipidemic nondiabetic patients: A comparative study [PDF]

open access: yesPharmacia, 2023
Background: Statins have emerged as a vital therapeutic option for dyslipidemia, effectively reducing morbidity and mortality in individuals with various medical conditions.
Hany A. Al-hussaniy   +3 more
doaj   +3 more sources

A multistate transition model for statin‐induced myopathy and statin discontinuation

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2021
The overarching goal of this study was to simultaneously model the dynamic relationships among statin exposure, statin discontinuation, and potentially statin‐related myopathic outcomes.
Yuxi Zhu   +9 more
doaj   +1 more source

Statin use and cognitive function: population-based observational study with long-term follow-up. [PDF]

open access: yesPLoS ONE, 2015
We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0-10;
Hanneke Joosten   +6 more
doaj   +1 more source

Impact of metformin on statin‐associated myopathy risks in dyslipidemia patients

open access: yesPharmacology Research & Perspectives, 2023
A growing number of patients with metabolic disorders are receiving statin and antidiabetic therapies as comedications. A signal of increased risk of myotoxicity due to potential interactions between antidiabetics and statins has been detected in ...
Keunhyeong Bak   +4 more
doaj   +1 more source

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort

open access: yesCardiovascular Diabetology, 2022
Background Prior studies of the glycemic effect of statins have been inconsistent. Also, most studies have only considered a short duration of statin use; the effect of long-term statin use on fasting glucose (FG) has not been well examined.
Tanushree Haldar   +7 more
doaj   +1 more source

Statin Therapy Is Associated With a Lower Risk of Heart Failure in Patients With Atrial Fibrillation: A Population‐Based Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Whether statin use can reduce the risk of heart failure (HF) remains controversial. The present study evaluates the association between statin use and HF in patients with atrial fibrillation.
Jia‐Yi Huang   +15 more
doaj   +1 more source

Comparative Analysis of High-Intensity versus Low-to-Moderate Intensity Statin Therapy in Patients Undergoing Rotational Atherectomy for Calcified Coronary Artery Disease

open access: yesLife, 2023
(1) Background: Moderate-intensity statin therapy, when compared to high-intensity statin therapy in Asian populations, has shown no significant difference in cardiovascular prognosis in small studies.
Sang-Suk Choi   +17 more
doaj   +1 more source

Statin use and the risk of hepatocellular carcinoma among patients with chronic hepatitis B: an emulated target trial using longitudinal nationwide population cohort data

open access: yesBMC Gastroenterology, 2023
Background No randomized controlled trials have been completed to see whether statin can decrease hepatocellular carcinoma (HCC) risk in chronic hepatitis B (CHB) patients.
Dong Hyun Sinn   +6 more
doaj   +1 more source

Statin use and cognitive function: population-based observational study with long-term follow-up.

open access: yesPLoS ONE, 2014
We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0-10;
Hanneke Joosten   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy