Results 31 to 40 of about 227,662 (304)

2019 Taiwan Society of Lipids and Atherosclerosis expert consensus statement on statin intolerance

Journal of the Formosan Medical Association, 2019
Statin reduces low-density lipoprotein cholesterol and improves clinical outcomes in high risk patients. In general, statin is a safe and well-tolerated medication.
Shih-Chieh Chien, Po-Sheng Chen, Yi-Hsiang Huang, Sung-Chun Tang, Yi-Heng Li, Hung-I Yeh   +5 more
doaj   +1 more source

Pharmacist-Led Programs to Increase Statin Prescribing: A Narrative Review of the Literature

Pharmacy, 2022
Statins are lipid-lowing medications shown to reduce cardiovascular events and are recommended for specific patient populations at elevated risk of atherosclerotic cardiovascular disease (ASCVD).
Mary Elkomos, Raha Jahromi, Michael S. Kelly   +2 more
doaj   +1 more source

Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study. [PDF]

, 2017
Background: Published evidence indicates that individual use of metformin and statin is associated with reduced cancer mortality. However, their differential and joint effects on pancreatic cancer survival are inconclusive.Methods: We identified a large ...
Demissie, Kitaw, E, Jian-Yu, Graber, Judith M., Lin, Yong, Lu, Shou-En, Lu-Yao, Grace, Petersen, Gloria M., Rotter, David, Tan, Xiang-Lin, Zhang, Lanjing   +9 more
core   +2 more sources

Utilization of Statins Beyond the Initial Period After Stroke and 1‐Year Risk of Recurrent Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundIn‐hospital discontinuation of statins has been linked to poorer early stroke outcomes, but the consequences of postdischarge discontinuation or dose reduction of statin treatment are unknown.
Meng Lee, Jeffrey L. Saver, Yi‐Ling Wu, Sung‐Chun Tang, Jiann‐Der Lee, Neal M. Rao, Hui‐Hsuan Wang, Jiann‐Shing Jeng, Tsong‐Hai Lee, Pei‐Chun Chen, Bruce Ovbiagele   +10 more
doaj   +1 more source

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. [PDF]

, 2020
In pharmacogenomic studies of quantitative change, any association between genetic variants and the pretreatment (baseline) measurement can bias the estimate of effect between those variants and drug response.
Haldar, Tanushree, Hoffmann, Thomas J, Iribarren, Carlos, Krauss, Ronald M, Medina, Marisa W, Oni-Orisan, Akinyemi, Ranatunga, Dilrini K, Risch, Neil, Schaefer, Catherine   +8 more
core   +2 more sources

Assessment of factors related to statin non-adherence in patients with established coronary artery disease: A single-center observational study

Türk Kardiyoloji Derneği Arşivi, 2017
Objective: Lifelong statin treatment is recommended in patients with cardiovascular diseases, but drug adherence is a significant problem. The aim of this study was to investigate factors related to statin discontinuation in high-risk patients with ...
Tuba Özdemir, İrfan Şahin, İlhan İlker Avcı, Barış Güngör, Eser Durmaz, Sevil Tuğrul, Mert İlker Hayıroğlu, Serdar Kahyaoğlu, Orkhan Karımov, Ertuğrul Okuyan   +9 more
doaj   +1 more source

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]

, 2015
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M, Casas, J-P, Chaturvedi, N, Fatemifar, G, Hingorani, AD, Hughes, AD, Jarvelin, M-R, Kahonen, M, Kangas, AJ, Kettunen, J, Kivimaki, M, Lawlor, DA, Lehtimaki, T, Mantyselka, P, Perola, M, Raitakari, OT, Salomaa, V, Sattar, N, Smith, GD, Soininen, P, Tiainen, M, Tillin, T, Tynkkynen, T, Vanhala, M, Wang, Q, Wurtz, P   +25 more
core   +2 more sources

Statin Intolerance

Reviews in Cardiovascular Medicine, 2018
Statins are critical medications to prevent and treat cardiovascular disease2 and they are generally very well tolerated. In some instances, however, statin intolerance may limit use of these lifesaving medications. Statin intolerance has many definitions but is commonly diagnosed when a patient is unable to continue statin therapy due to perceived, or
Alan S, Brown, Karol E, Watson
openaire   +2 more sources

Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. [PDF]

, 2017
BackgroundAlthough HIV is associated with increased atherosclerotic cardiovascular disease (CVD) risk, it is unknown whether guidelines can identify HIV-infected adults who may benefit from statins.
Deeks, Steven, Hsue, Priscilla, Hur, Sophia, Kalapus, SC, Li, Danny, Ma, Yifei, Phan, Binh An P, Scherzer, Rebecca, Weigel, Bernard   +8 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source