Results 21 to 30 of about 227,662 (304)

The Different Cardiovascular Outcomes Between Long-Term Efficacy of Hydrophilic and Lipophilic Statin Therapy in Both Asian Diabetic Sexes

Dose-Response, 2019
Purpose: To evaluate the long-term efficacy of hydrophilic and lipophilic statin therapy for cardiovascular outcomes in Asian diabetic patients. Method: Newly diagnosed cases of type 2 diabetes during the period from January 2000 to December 2011 were ...
Shang-Yi Li, Hsin-Hung Chen, Cheng-Li Lin, Su-Yin Yeh, Chia-Hung Kao   +4 more
doaj   +1 more source

Association of PCSK9 Inhibitor Initiation on Statin Adherence and Discontinuation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background PCSK9is (proprotein convertase subtilisin/kexin type 9 inhibitors) are well tolerated, potently lower cholesterol, and decrease cardiovascular events when added to statins.
Christopher LaFratte, Samuel K. Peasah, Yan Huang, Deanne Hall, Urvashi Patel, Chester B. Good   +5 more
doaj   +1 more source

Geographic variation in statin use for complex acute myocardial infarction patients: evidence of effective care? [PDF]

, 2014
Reprinted with permission of publisher.BACKGROUND: Despite strong evidence to designate statin use for secondary prevention of cardiovascular disease (CVD) as "effective care," observational studies show that many patients with CVD do not receive statins.
Abd, Armitage, Armitage, Fang, Fang, Florentin, Golomb, Ickowicz, Law, Lee, Nallamothu, Nichols, Robinson, Robinson, Sathasivam, Thompson, Wallace   +16 more
core   +1 more source

Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records

Frontiers in Genetics, 2021
Background: Statin intolerance impacts approximately 10% of statin users, with side effects ranging from mild myalgia to extreme intolerance resulting in myopathy and rhabdomyolysis.
Alaa’ Lutfi Melhem, Mehul Kumar Chourasia, Margherita Bigossi, Margherita Bigossi, Cyrielle Maroteau, Alasdair Taylor, Roberto Pola, Adem Y. Dawed, Aleksi Tornio, Aleksi Tornio, Colin N. A. Palmer, Moneeza K. Siddiqui   +11 more
doaj   +1 more source

Statin Therapy and Symptom Burden in Patients With Fibromyalgia: A Prospective Questionnaire Study

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2021
Objective: To evaluate the association between statin use and symptom severity, tender point count, fatigue, cognition, mood, and sleep issues in patients with fibromyalgia (FM).
Ryan S. D’Souza, MD, Mary O. Whipple, PhD, Ann Vincent, MD   +2 more
doaj   +1 more source

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N, Farjami, Sassan, Kaiser, Cassandra J, Leung, Anthony, Romansky, Stephen, Strube, Sarah J, Sweidan, Alexander J   +6 more
core   +3 more sources

UJI KLINIS TERBUKA EFEK TERAPI STATIN (SIMVASTATIN) TERHADAP KADAR HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) PADA PENDERITA DIABETES TIPE 2

Saintika Medika, 2012
Latar Belakang. Diabetes mellitus (DM) mempunyai resiko kematian karena penyakit kardiovaskular dua sampai enam kali dibanding pasien tanpa DM. diketahui bahwa inflamasi berperan dalam pathogenesis aterosklerosis.
Isbandiyah .
doaj   +1 more source

Trends and outcome of statin therapy in dialysis patients with atherosclerotic cardiovascular diseases: A population-based cohort study.

PLoS ONE, 2023
BackgroundAlthough statins are an effective strategy for the secondary prevention of atherosclerotic cardiovascular disease (ASCVD) in the general population, the benefits for dialysis patients are controversial.
Myunhee Lee, Yu Ah Hong, Jun-Pyo Myong, Kyusup Lee, Mahn-Won Park, Dae-Won Kim   +5 more
doaj   +1 more source

Effect of Concomitant 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor Therapy on Creatine Phosphokinase Levels and Mortality Among Patients Receiving Daptomycin: Retrospective Cohort Study. [PDF]

, 2014
IntroductionThe prescribing information for daptomycin recommends discontinuing statin therapy during receipt of daptomycin. The literature supporting this recommendation is sparse.
Lodise, Thomas, Lowry, Colleen, McConnell, Heather L, Patel, Nimish, Perris, Elizabeth T   +4 more
core   +1 more source

A Pilot Study: The Beneficial Effects of Combined Statin-exercise Therapy on Cognitive Function in Patients with Coronary Artery Disease and Mild Cognitive Decline. [PDF]

, 2017
Objective Hypercholesterolemia, a risk factor in cognitive impairment, can be treated with statins. However, cognitive decline associated with "statins" (HMG-CoA reductase inhibitors) is a clinical concern.
Hamada, Mari, Horio, Eiji, Iwasaki, Yuri, Nakamura, Shinichi, Ogawa, Hisao, Oka, Hideki, Rokutanda, Taku, Spin, Joshua M, Sugiyama, Seigo, Toyama, Kensuke, Tsao, Philip S   +10 more
core   +1 more source