British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh +5 more
wiley +1 more source
Prevalence of substances with OATP1B1 inhibitory properties in individual case safety reports of suspected statin-associated myopathy - an analysis of Swiss pharmacovigilance data. [PDF]
Eur J Clin PharmacolStäuble CK +4 more
europepmc +1 more source
Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes +7 more
wiley +1 more source
Alzheimer's disease in patients prescribed statins: A real-world data analysis of U.S. patient health records. [PDF]
J Alzheimers DisNovak DA +7 more
europepmc +1 more source
Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery
Clinical Endocrinology, EarlyView.ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues +7 more
wiley +1 more source
Current perspectives on lipid management in diabetic kidney disease: Can fibrates offer advantages over statins for renal outcomes? [PDF]
J Res Med SciChitsazi MR +9 more
europepmc +1 more source
Clinical Oral Implants Research, EarlyView.ABSTRACT Objectives This retrospective study primarily evaluated whether early radiographic bone loss (ERBL) predicts progressive bone loss (PBL), and secondarily assessed its association with implant survival and peri‐implant diseases. Methods Adults with dental implants who were followed for at least 5 years were included.
Dominick Moser +8 more
wiley +1 more source
Statin prescription patterns among patients with type 2 diabetes mellitus for primary and secondary prevention of cardiovascular disease. [PDF]
BMC Endocr DisordAbdelaal AM +4 more
europepmc +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Introduction Disseminated superficial actinic porokeratosis (DSAP) is a rare keratinization disorder associated with an increased risk of cutaneous tumors. Objectives To develop a feasible and easy‐to‐apply treatment regimen for long‐time disease control of DSAP including prevention of new skin tumors. Patients and Methods 19 patients with DSAP
Berenice M. Lang +6 more
wiley +1 more source