Results 251 to 260 of about 150,085 (313)

Proteomic Profiling Captures Residual Cardiovascular Risk Beyond the PREVENT Model in Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 2–3

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome reflects complex pathobiological interactions among metabolic disorders, kidney injury, and cardiovascular disease (CVD). Stages 2 and 3 represent critical phases of disease progression characterised by high pathological heterogeneity.
Xuefei Han   +4 more
wiley   +1 more source

Empagliflozin Versus Dapagliflozin and Urogenital Adverse Events in Type 2 Diabetes: A Target Trial Emulation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Urogenital adverse events are common with sodium‐glucose co‐transporter 2 inhibitors (SGLT2i) and may influence treatment decisions. Variations in SGLT2i selectivity, potency and effects on renal glucose excretion could lead to differences in safety profiles. We compared the risks of urinary tract infection (UTI), genital tract infection (
Christine Ljungberg   +7 more
wiley   +1 more source

Editorial: New drugs in lipid lowering therapy. [PDF]

open access: yesFront Cardiovasc Med
Bytyçi I, Banach M, Pećin I.
europepmc   +1 more source

Comparative Effects of Emerging Lp(a)‐Lowering Agents and PCSK9‐Directed Therapies on Lipoprotein(a): A Network Meta‐Analysis of Randomised Clinical Trials

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Elevated lipoprotein(a) [Lp(a)] is a genetic ASCVD risk factor that often persists despite intensive LDL‐C lowering. We compared the efficacy and safety of emerging Lp(a)‐targeted therapies (siRNAs, antisense oligonucleotides and an oral assembly inhibitor) with PCSK9‐directed therapies.
Jihad Abu Zayed   +4 more
wiley   +1 more source

Greater Glycaemic Responses to Bodyweight Change in South Asians Than White Europeans at High Risk of Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Bodyweight change is an important determinant of cardiometabolic health, but its metabolic impact may differ by ethnicity. This study investigated whether ethnicity (White European, South Asian) modifies the association between change in bodyweight and changes in HbA1c and oral glucose tolerance test (OGTT)–derived measures. Materials and
Franciskos Arsenyadis   +5 more
wiley   +1 more source

The therapeutic potential of atorvastatin in treatment of <i>G. lamblia</i> infected mice; <i>in silico</i>, parasitological, and histopathological study. [PDF]

open access: yesFront Vet Sci
Mohamed K   +8 more
europepmc   +1 more source

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