Stress-Inducible Transcription Factor NUPR1 Is Involved in the Inhibitory Effects Exerted by Statins on Insulin Action in ER-Positive Breast Cancer Cells. [PDF]
Scordamaglia D +7 more
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Novel Approaches to Lipid Management: Beyond Statins and PCSK9 Inhibitors. [PDF]
Patel J +5 more
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Statin therapy and stroke risk in patients with hypercholesterolaemia: a population-based longitudinal study using electronic health records in South London. [PDF]
Delord M, Douiri A.
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The effect of medication use on chronic pruritus in patients with type 2 diabetes mellitus: a multicenter cross-sectional study. [PDF]
Xu M +10 more
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Dyslipidemia in Diabetes: Navigating a Complex Landscape for Improved Cardiovascular Outcomes. [PDF]
Abdul Wahab R, Wan Mahmood WA.
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Statin Therapy and Clinical Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis. [PDF]
Gillani I +7 more
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Clinical studies have shown that hydroxy-methyl glutaryl coenzyme A reductase inhibitors (statins) may favorably affect atherothrombosis. In addition to their potent cholesterol-lowering properties, statins reduce atheroma progression as well as the incidence of acute thrombosis-related vascular events and their dreadful clinical consequences ...
S. Colli, J. P. Werba, E. Tremoli
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Lipid lowering, particularly with 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors ("statins"), reduces the risk of cardiovascular disease. Patients with chronic liver disease present challenges to the use of lipid medications. In the case of most liver disorders, the concern has been one of safety.
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A statin is first-line drug therapy for dyslipidemia. Clinical trial data suggest there is an increase in the incidence of new-onset type 2 diabetes mellitus with statin use. The National Lipid Association (NLA) Statin Diabetes Safety Task Force concluded that the cardiovascular benefit of statin therapy outweighs the risk for developing diabetes.
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