Results 91 to 100 of about 13,417,468 (277)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Statistical hadronization with resonances

, 2004
We introduce the equilibrium and non-equilibrium statistical hadronization picture of particle production in ultra-relativistic heavy ion collisions. We describe the related physical reaction scenarios, and show how these can lead to quark pair yield non-
Letessier, Jean, Rafelski, Johann, Steinke, Steve, Torrieri, Giorgio   +3 more
core   +1 more source

Covariant Equilibrium Statistical Mechanics

, 2006
A manifest covariant equilibrium statistical mechanics is constructed starting with a 8N dimensional extended phase space which is reduced to the 6N physical degrees of freedom using the Poincare-invariant constrained Hamiltonian dynamics describing the ...
Barut A. O., de Groot S. R., E. Lehmann, Gitman D. M., Gradsteyn I. S., Hanson A., Havas P., Henneaux M., Horwitz L. P., Huang K., Münster A., Stückelberg E. C. G., Sundermeyer K.   +12 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Common Dietary Patterns Among Female Employees Participating in the Persian Cohort Study (Mashhad) and Their Relationship With Metabolic Syndrome

Health Science Reports
Background The protective effect of a healthy diet against chronic diseases has been confirmed in several primary studies. This study identifies the dominant food patterns using factor analysis and determining its relationship with metabolic syndrome in ...
Fatemeh Davoudi Dastenaie, Fatemeh Sadat Hashemi Javaheri, Mohammad Masoumvand, Mohammad Amin Nazari Manesh, Mohammad Akbari Moghadam, Maryam Khosravi, Ali Jafarzadeh Esfehani   +6 more
doaj   +1 more source

Statistical properties and statistical interaction for particles with spin: Hubbard model in one dimension and statistical spin liquid

, 1994
We derive the statistical distribution functions for the Hubbard chain with infinite Coulomb repulsion among particles and for the statistical spin liquid with an arbitrary magnitude of the local interaction in momentum space.
D.V. Khveshchenko, E.H. Lieb, F.D.M. Haldane, J. Carmelo, J. Carmelo, J. Hubbard, J. Spałek, J. Spałek, J. Spałek, J. Spałek, J. Spałek, J. Spałek, J.B. Sokoloff, J.M. Leinaas, Jozef Spal/ek, K. Byczuk, Krzysztof Byczuk, M. Ogata, M.V.N. Murthy, N. Andrei, P.M. Chaikin, P.W. Anderson, P.W. Anderson, Y. Hatsugai   +23 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Evaluation of prognostic models to improve prediction of metastasis in patients following potentially curative treatment for primary colorectal cancer: the PROSPECT trial

Health Technology Assessment
Background Despite apparently curative treatment, many patients with colorectal cancer develop subsequent metastatic disease. Current prognostic models are criticised because they are based on standard staging and omit novel biomarkers.
Vicky Goh, Susan Mallett, Manuel Rodriguez-Justo, Victor Boulter, Rob Glynne-Jones, Saif Khan, Sarah Lessels, Dominic Patel, Davide Prezzi, Stuart Taylor, Steve Halligan   +10 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source