Results 261 to 270 of about 13,510,761 (277)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Genetic parameters estimation and optimization of genomic selection in mud crab (Scylla paramamosain): a case study for growth-related traits. [PDF]

BMC Genomics
Zhou X, Hong Z, Cui W, Zhang Y, Ikhwanuddin M, Ye S, Ma H.   +6 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Under my umbrella: Rating scales obscure statistical power and effect size heterogeneity. [PDF]

Behav Res Methods
Fünderich JH, Beinhauer LJ, Renkewitz F.   +2 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Statistical Power in Musculoskeletal Research: A Meta-Review of 266 Randomised Controlled Trials. [PDF]

Sports Med Open
Bleakley C, Klempel N, Wagemans J, Netterström-Wedin F, Smoliga J.   +4 more
europepmc   +1 more source

EnhancedBERT: A feature-rich ensemble model for Arabic word sense disambiguation with statistical analysis and optimized data collection

Sanaa Kaddoura, Reem Nassar
openalex   +1 more source

CircCdh7 induces astrogliosis and neuroinflammation to trigger hypertensive effects in the rostral ventrolateral medulla. [PDF]

Cell Biosci
Zhang S, Dai T, Zhao B, Wang X, Wang L, Tong L, Zeng Q, He Q, Zhang H, Du D.   +9 more
europepmc   +1 more source

Impact of deep learning based reconstruction algorithms on CT radiomic features of carotid plaques. [PDF]

J Appl Clin Med Phys
Wang H, Xu J, Ye C, Sun A, Liu J, Wang S, Zheng X, Cao G.   +7 more
europepmc   +1 more source