Results 81 to 90 of about 17,333,893 (364)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Data Structures for Statistical Computing in Python

open access: yesSciPy, 2010
In this paper we are concerned with the practical issues of working with data sets common to finance, statistics, and other related fields. pandas is a new library which aims to facilitate working with these data sets and to provide a set of fundamental ...
Wes McKinney
semanticscholar   +1 more source

Statistical Reconstruction of Qutrits

open access: yes, 2004
We discuss a procedure of measurement followed by the reproduction of the quantum state of a three-level optical system - a frequency- and spatially degenerate two-photon field.
A. A. Zhukov   +15 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Fluctuations in statistical models [PDF]

open access: yes, 2007
Proceedings of 4th International Workshop "Critical Point and Onset of Deconfinement", July 9-13, 2007, Darmstadt, Germany: The multiplicity fluctuations of hadrons are studied within the statistical hadron-resonance gas model in the large volume limit ...
Gorenstein, Mark I.
core   +1 more source

Statistical Physics in Meteorology

open access: yes, 2004
Various aspects of modern statistical physics and meteorology can be tied together. The historical importance of the University of Wroclaw in the field of meteorology is first pointed out.
Andrade   +70 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Factorial structure and construct validity of an iranian version of the fear of compassion scale: A study in nurses

open access: yesIranian Journal of Nursing and Midwifery Research, 2020
Backgrounds: Fear of compassion is one of the psychological variables in the nursing profession that can be a barrier to providing appropriate services to patients.
Sajad Khanjani   +5 more
doaj   +1 more source

Statistical mechanics of money

open access: yes, 2000
In a closed economic system, money is conserved. Thus, by analogy with energy, the equilibrium probability distribution of money must follow the exponential Gibbs law characterized by an effective temperature equal to the average amount of money per ...
Dragulescu, Adrian, Yakovenko, Victor M.
core   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

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