Results 81 to 90 of about 17,333,893 (364)
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Data Structures for Statistical Computing in Python
In this paper we are concerned with the practical issues of working with data sets common to finance, statistics, and other related fields. pandas is a new library which aims to facilitate working with these data sets and to provide a set of fundamental ...
Wes McKinney
semanticscholar +1 more source
Statistical Reconstruction of Qutrits
We discuss a procedure of measurement followed by the reproduction of the quantum state of a three-level optical system - a frequency- and spatially degenerate two-photon field.
A. A. Zhukov+15 more
core +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona+4 more
wiley +1 more source
Fluctuations in statistical models [PDF]
Proceedings of 4th International Workshop "Critical Point and Onset of Deconfinement", July 9-13, 2007, Darmstadt, Germany: The multiplicity fluctuations of hadrons are studied within the statistical hadron-resonance gas model in the large volume limit ...
Gorenstein, Mark I.
core +1 more source
Statistical Physics in Meteorology
Various aspects of modern statistical physics and meteorology can be tied together. The historical importance of the University of Wroclaw in the field of meteorology is first pointed out.
Andrade+70 more
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Backgrounds: Fear of compassion is one of the psychological variables in the nursing profession that can be a barrier to providing appropriate services to patients.
Sajad Khanjani+5 more
doaj +1 more source
Statistical mechanics of money
In a closed economic system, money is conserved. Thus, by analogy with energy, the equilibrium probability distribution of money must follow the exponential Gibbs law characterized by an effective temperature equal to the average amount of money per ...
Dragulescu, Adrian, Yakovenko, Victor M.
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source