Results 91 to 100 of about 3,413,020 (302)

The Empirical Saddlepoint Approximation for GMM Estimators [PDF]

The empirical saddlepoint distribution provides an approximation to the sampling distributions for the GMM parameter estimates and the statistics that test the overidentifying restrictions.
Sowell, Fallaw
core  

Statistical analysis of alignment characteristics for phrase-based machine translation [PDF]

, 2010
In most statistical machine translation (SMT) systems, bilingual segments are extracted via word alignment. However, there lacks systematic study as to what alignment characteristics can benefit MT under specific experimental settings such as the ...
Petitrenaud, Simon, Patrik Lambert, Andy Way, Lambert, Patrik, Way, Andy, Yanjun Ma, Simon Petitrenaud, Ma, Yanjun   +7 more
core   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Approximation using Jakimovski–Leviatan operators of Durrmeyer type with 2D-Appell polynomials

Journal of Inequalities and Applications
This article delves into Jakimovski–Leviatan–Durrmeyer type operators based on 2D-Appell polynomials. The investigation initiates by exploring the Korovkin-type approximation theorem and its convergence rates, employing both the traditional modulus of ...
Manoj Kumar, Nusrat Raza, M. Mursaleen
doaj   +1 more source

Significance evaluation in factor graphs

BMC Bioinformatics, 2017
Background Factor graphs provide a flexible and general framework for specifying probability distributions. They can capture a range of popular and recent models for analysis of both genomics data as well as data from other scientific fields.
Tobias Madsen, Asger Hobolth, Jens Ledet Jensen, Jakob Skou Pedersen   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Approximation theorems using the method of $\mathcal{I}_{2}$-statistical convergence

Journal of Amasya University the Institute of Sciences and Technology
In this study, we utilize the concept of $\mathcal{I}$-statistical convergence for double sequences to establish a general approximation theorem of Korovkin-type for double sequences of positive linear operators $(PLOs)$ mapping from $H_{\omega }\left( X\
Sevda Yıldız, Kamil Demirci, Fadime Dirik   +2 more
doaj   +1 more source

An Improved Approximation to the Distributions in GMM Estimation [PDF]

The empirical saddlepoint distribution provides an approximation to the sampling distributions for the GMM parameter estimates and the statistics that test the overidentifying restrictions.
Fallaw Sowell
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Poisson approximation of binomial point processes [PDF]

E3S Web of Conferences
In the paper, we study properties of the vertex process from convex hulls generated by independent observations of a two-dimensional random vector, the distribution of which behaves like a regularly varying function near the boundary of the support of ...
Khamdamov Isakjan, Sharipova Lola
doaj   +1 more source