Results 71 to 80 of about 3,413,020 (302)

Testing the Approximate Validity of Statistical Hypotheses [PDF]

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1954
Summary The distinction between statistical significance and material significance in hypotheses testing is discussed. Modifications of the customary tests, in order to test for the absence of material significance, are derived for several parametric problems, for the chi-square test of goodness of fit, and for Student’s hypothesis.
Hodges, J. L. jun., Lehmann, E. L.
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Stein's method and Poisson process approximation for a class of Wasserstein metrics

, 2009
Based on Stein\’s method, we derive upper bounds for Poisson process approximation in the L1-Wasserstein metric d (p) 2 , which is based on a slightly adapted Lp-Wasserstein metric between point measures.
Schuhmacher, Dominic
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Approximate Bayesian computation with functional statistics [PDF]

Statistical Applications in Genetics and Molecular Biology, 2013
Functional statistics are commonly used to characterize spatial patterns in general and spatial genetic structures in population genetics in particular. Such functional statistics also enable the estimation of parameters of spatially explicit (and genetic) models.
Soubeyrand, Samuel, Carpentier, Florence, Guiton, François, Klein, Etienne K.   +3 more
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Statistical significance approximation for local similarity analysis of dependent time series data

BMC Bioinformatics, 2019
Background Local similarity analysis (LSA) of time series data has been extensively used to investigate the dynamics of biological systems in a wide range of environments.
Fang Zhang, Fengzhu Sun, Yihui Luan
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Statistical Process Control for Unimodal Distribution Based on Maximum Entropy Distribution Approximation

Entropy, 2017
In statistical process control, the control chart utilizing the idea of maximum entropy distribution density level sets has been proven to perform well for monitoring the quantity with multimodal distribution.
Xinghua Fang, Mingshun Song, Yizeng Chen
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source