Results 81 to 90 of about 356,980 (295)
Maximin and maximin-efficient event-related fMRI designs under a nonlinear model
, 2013 Previous studies on event-related functional magnetic resonance imaging experimental designs are primarily based on linear models, in which a known shape of the hemodynamic response function (HRF) is assumed.
Kao, Ming-Hung +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Agronomía Colombiana, 1994 Scientilic papers of six wellknown international journal of agricultural research (Agronomy Journal, Crop Science, Plant Physiology, Phytopathology, Plant Disease, Journal of Economic Entomology) and the Revista ICA of Colombia, were revised taking the ...
Martínez W. Orlando, Galindo Ricardo
doaj
There Once Was a 9-Block …- A Middle-School Design for Probability and Statistics
Journal of Statistics Education, 2006 ProbLab is a probability-and-statistics unit developed at the Center for Connected Learning and Computer-Based Modeling, Northwestern University.
Dor Abrahamson +2 more
openaire +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The impact of randomization techniques on the performance of pre-post design models
BMC Medical Research MethodologyPre-post designs are widely used in clinical trials and experimental studies to assess the effectiveness of treatments. Common statistical methods for analyzing pre-post data include analysis of variance (ANOVA) using post-treatment or the change from ...
Xinlin Lu +3 more
doaj +1 more source
Introduction to fMRI: experimental design and data analysis [PDF]
, 2008 This provides an introduction to functional MRI, experimental design and data analysis procedures using statistical parametric mapping ...
Miyapuram, Krishna P.
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
On the understanding of zinc-oxide eugenol cement use prior to etch-rinse bonding strategies
Indian Journal of Dental Research, 2019 Context: Zinc-oxide eugenol (ZOE) is frequently used due to its satisfactory biological response, sedative effect on the pulp, and easy removal. However, literature is very controversial about the influence of the temporary cement-containing eugenol on ...
Catarina Pires Bezerra +6 more
doaj +1 more source