Results 61 to 70 of about 58,673 (265)

An analytical review of statistical methods and designs in agricultural science Una revisión analítica de diseños y métodos estadísticos en ciencias agrícolas

open access: yesAgronomía Colombiana, 1994
Scientilic papers of six wellknown international journal of agricultural research (Agronomy Journal, Crop Science, Plant Physiology, Phytopathology, Plant Disease, Journal of Economic Entomology) and the Revista ICA of Colombia, were revised taking the ...
Martínez W. Orlando, Galindo Ricardo
doaj  

Relative efficiency of the alpha lattice and randomized complete block designs in maize trials [PDF]

open access: yesPesquisa Agropecuária Brasileira
The objective of this work was to compare the relative efficiency of the alpha lattice design (ALD) with that of the randomized complete block design (RCBD) in maize (Zea mays) genotype trials. For this, data from 627 trials were used.
Román Gordón Mendoza   +2 more
doaj   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The impact of randomization techniques on the performance of pre-post design models

open access: yesBMC Medical Research Methodology
Pre-post designs are widely used in clinical trials and experimental studies to assess the effectiveness of treatments. Common statistical methods for analyzing pre-post data include analysis of variance (ANOVA) using post-treatment or the change from ...
Xinlin Lu   +3 more
doaj   +1 more source

Effects of different building blocks designs on the statistical characteristics of Automated Zone-design Tool output areas

open access: yesSouth African Journal of Geomatics, 2017
Prior to any census, the country usually gets demarcated into small geographic units called census enumeration areas, districts or blocks. In most countries, these small geographic units are also used for census dissemination. In cases where they are not used for census release, they are normally used as building blocks for developing output areas or ...
Mokhele, T, Mutanga, O, Ahmed, F
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

On the understanding of zinc-oxide eugenol cement use prior to etch-rinse bonding strategies

open access: yesIndian Journal of Dental Research, 2019
Context: Zinc-oxide eugenol (ZOE) is frequently used due to its satisfactory biological response, sedative effect on the pulp, and easy removal. However, literature is very controversial about the influence of the temporary cement-containing eugenol on ...
Catarina Pires Bezerra   +6 more
doaj   +1 more source

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