Results 51 to 60 of about 359,562 (292)
Optimal experimental designs for fMRI via circulant biased weighing designs
, 2015 Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise statistical inference ...
Cheng, Ching-Shui, Kao, Ming-Hung
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Cephalometric Comparison of a Modified Bionator (Farmand Appliance) and Twin-Block Appliance in Treatment of Skeletal Cl II Malocclusion [PDF]
Iranian Journal of Orthodontics, 2014 background and aim: functional appliances with various designs have been introduced in the treatment of Class II malocclusions. The aim of this study was to evaluate dentoskeletal effects of a modified bionator (FA) and Twin Block (TB) functional ...
Mohammad Karim Soltani +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Evaluating Algorithm Efficiency for Optimizing Experimental Designs with Correlated Data
Algorithms, 2018 The search for efficient methods and procedures to optimize experimental designs is a vital process in field trials that is often challenged by computational bottlenecks.
Lazarus K. Mramba, Salvador A. Gezan
doaj +1 more source
Statistical aspects of experimental designs implemented in designs [PDF]
, 2003 The report describes the statistical aspects of experimental designs used in an ...
Kristensen, K.
core
A general theory of minimum aberration and its applications
, 2005 Minimum aberration is an increasingly popular criterion for comparing and assessing fractional factorial designs, and few would question its importance and usefulness nowadays.
Cheng, Ching-Shui, Tang, Boxin
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Resolvable designs with large blocks
, 2007 Resolvable designs with two blocks per replicate are studied from an optimality perspective. Because in practice the number of replicates is typically less than the number of treatments, arguments can be based on the dual of the information matrix and ...
Morgan, J. P., Reck, Brian H.
core +2 more sources