Results 111 to 120 of about 4,030,414 (327)
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Indian Journal of Psychological Medicine, 2019 The calculation of a P value in research and especially the use of a threshold to declare the statistical significance of the P value have both been challenged in recent years.
C. Andrade
semanticscholar +1 more source
Strengthening pharmacy practice: Development and validation of the Resilience Scale [PDF]
Vojnosanitetski PregledBackground/Aim. Despite the demanding nature of their roles in community pharmacies and their critical importance to patient safety, healthcare professionals, including pharmacists, are often not covered by the Resilience Scale. Therefore, the aim of the
Jocić Dragana
doaj +1 more source
Neural nets - their use and abuse for small data sets [PDF]
, 2000 Neural nets can be used for non-linear classification and regression models. They have a big advantage over conventional statistical tools in that it is not necessary to assume any mathematical form for the functional relationship between the variables.
Meyer, Denny
core
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Prognostic factors in exacerbated chronic obstructive pulmonary disease
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021 Background: chronic obstructive pulmonary disease has a high prevalence worldwide. It is important to know the mechanisms that have an influence on the high mortality of the exacerbated form of the disease.Objective: to identify the prognostic factors ...
Iraibis Rodríguez-Pérez +3 more
doaj
Likelihood-based statistical estimation from quantized data [PDF]
Most standard statistical methods treat numerical data as if they were real (infinitenumber- of-decimal-places) observations. The issue of quantization or digital resolution is recognized by engineers and metrologists, but is largely ignored by ...
Lee, Chiang-Sheng, Vardeman, Stephen B.
core
Hypothesis Testing Interpretations and Renyi Differential Privacy [PDF]
, 2019 Differential privacy is a de facto standard in data privacy, with applications in the public and private sectors. A way to explain differential privacy, which is particularly appealing to statistician and social scientists is by means of its statistical ...
Balle, Borja +4 more
core
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Análisis interino en ensayos clínicos: un estudio meta-epidemiológico
Medicina U.P.B., 2017 Objetivo: la responsabilidad ética del investigador obliga al monitoreo de la seguridad de los participantes a través del estudio y, por ende, se requiere de un comité de moni-toreo de datos, cuya tarea principal es el análisis interino que se refiere a ...
Laura Acevedo Ortiz +2 more
doaj +1 more source