Results 141 to 150 of about 4,193,923 (352)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Análise rotineira de dados de vigilância em saúde pública: que procedimentos estatísticos utilizar?

Revista de Saúde Pública
Tem havido no país, nos últimos anos, crescente interesse por questões vinculadas à área tradicionalmente denominada vigilância epidemiológica (que se denominou vigilância em saúde pública). Tem-se defendido, em muitas publicações, o ponto de vista que o
Odécio Sanches
doaj  

Usefulness of statistical implicative analysis to identify prognostic factors in patients with breast cancer

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: identifying prognostic factors in patients with breast cancer continues to be a necessity.Objective: to assess the usefulness of statistical implicative analysis to identify the prognostic factors which contribute to the progress of the ...
Surama Pardo-Santana, Nelsa María Sagaró-del-Campo, Larisa Zamora-Matamoros, Dulce María Viltre-Castellanos   +3 more
doaj  

Overcoming Missing Data: Accurately Predicting Cardiovascular Risk in Type 2 Diabetes, A Systematic Review

Journal of Diabetes
Understanding is limited regarding strategies for addressing missing value when developing and validating models to predict cardiovascular disease (CVD) in type 2 diabetes mellitus (T2DM). This study aimed to investigate the presence of and approaches to
Wenhui Ren, Keyu Fan, Zheng Liu, Yanqiu Wu, Haiyan An, Huixin Liu   +5 more
doaj   +1 more source

On the Provenance of Linked Data Statistics [PDF]

arXiv, 2014
As the amount of linked data published on the web grows, attempts are being made to describe and measure it. However even basic statistics about a graph, such as its size, are difficult to express in a uniform and predictable way. In order to be able to sensibly interpret a statistic it is necessary to know how it was calculate. In this paper we survey
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Analyzing Gensini Score as a Semi-Continuous Outcome

Journal of Tehran University Heart Center, 2016
Background: Investigators frequently encounter continuous outcomes with plenty of values clumped at zero called semi-continuous outcomes. The Gensini score, one of the most widely used scoring systems for expressing coronary angiographic results, is of ...
Homa Kashani, Hojjat Zeraati, Kazem Mohammad, Hamidreza Goodarzynejad, Mahmood Mahmoudi, Saeed Sadeghian, Mohammadali Boroumand   +6 more
doaj  

An empirical approach to demographic inference with genomic data [PDF]

arXiv, 2015
Inference with population genetic data usually treats the population pedigree as a nuisance parameter, the unobserved product of a past history of random mating. However, the history of genetic relationships in a given population is a fixed, unobserved object, and so an alternative approach is to treat this network of relationships as a complex object ...
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Hydrodynamic and Sediment Transport Patterns in the Minho and Douro Estuaries (NW Portugal) Based on ADCP Monitoring Data: Part 2—Statistical Interpretation of Bottom Moored Datasets [PDF]

, 2021
Ana I. Santos, Anabela Oliveira, Dora Carinhas, José Paulo Pinto, Maria Conceição Freitas   +4 more
openalex   +1 more source