Results 51 to 60 of about 167,868,153 (286)

Experiments All the Way:Diagrams of Dialectics between a Design Research program and Experiments

open access: yes, 2013
Experiments take various forms, have various purposes, and generate various knowledge, depending on how and when they are integrated into a design research study. In this paper, as reflective (co-) design researchers/practitioners, we exemplify and argue
Eriksen, Mette Agger,   +3 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Program R: applications in plant breeding

open access: yesCrop Breeding and Applied Biotechnology, 2011
Nowadays the demand for so-called free, or open source software for data analysis as well as the appeal to use it is great. An public domain software that has become extremely well-known, with ever-increasing numbers of fans and even co-workers, is ...
Luiz Alexandre Peternelli
doaj  

Planejamento estatístico de experimentos aplicado ao desenvolvimento de formulações para revestimentos cerâmicos Statistical design of experiments applied to the development of formulations for ceramic tiles

open access: yesCerâmica, 2004
Este trabalho avalia a utilização de técnicas de planejamento estatístico de experimentos com misturas envolvendo variáveis de processo no estudo de formulações para a produção de revestimentos cerâmicos, buscando minimizar o caráter empírico encontrado ...
R. T. Zauberas   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Perspective: the gist of public tender for service design [PDF]

open access: yes, 2018
Governments around the world are increasingly formalising design as an innovative approach to renew public services. In this development, the capabilities of external service design consultancies often play an important part, which calls for new insights
Person, Oscar   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Introducing Experience Goals into Packaging Design [PDF]

open access: yes, 2016
Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi   +3 more
core   +1 more source

Simulation Experiments in Practice: Statistical Design and Regression Analysis [PDF]

open access: yes
In practice, simulation analysts often change only one factor at a time, and use graphical analysis of the resulting Input/Output (I/O) data. The goal of this article is to change these traditional, naïve methods of design and analysis, because ...
Kleijnen, J.P.C.
core   +2 more sources

Optimization of Direct 2-propanol Fuel Cell Performance Using Statistical Design of Experiments Approach

open access: yesInternational Journal of Electrochemical Science, 2012
Direct alcohol fuel cells have been attracting enormous research interest as power sources for vehicles and portable electronic devices because alcohols are readily available, their storage and transport can be easily handled with the existing fuel ...
Arfat Anis   +2 more
doaj   +1 more source

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