Results 91 to 100 of about 419,428 (264)
The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling
Frontiers in Genetics, 2019 Pathway-centric approaches are widely used to interpret and contextualize -omics data. However, databases contain different representations of the same biological pathway, which may lead to different results of statistical enrichment analysis and ...
Sarah Mubeen +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
A novel methodological framework for testing automated vehicle functions
European Transport Research Review, 2020 Since there are more and more highly automated vehicles in road transportation with various extremely safety-critical functions, it is crucial to intensify the development of testing methods.
Árpád Török
doaj +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Teaching & Learning Inquiry: The ISSOTL Journal, 2016 Quantitative results from empirical studies are common in the field of Scholarship of Teaching and Learning (SoTL), but it is important to remain aware of what the results from our studies can, and cannot, tell us. Oftentimes studies conducted to examine
April McGrath
doaj +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
On testing the equality of high dimensional mean vectors with unequal covariance matrices [PDF]
arXiv, 2014 In this article, we focus on the problem of testing the equality of several high dimensional mean vectors with unequal covariance matrices. This is one of the most important problem in multivariate statistical analysis and there have been various tests proposed in the literature.
arxiv
A statistical test for periodicity hypothesis in the crater formation rate [PDF]
, 1991 S. Yabushita
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
A bootstrap test for equality of variances [PDF]
Computational Statistics & Data Analysis, Volume 54, Issue 10, 1
October 2010, Pages 2306-2316, 2018 We introduce a bootstrap procedure to test the hypothesis $H_o$ that $K+1$ variances are homogeneous. The procedure uses a variance-based statistic, and is derived from a normal-theory test for equality of variances. The test equivalently expressed the hypothesis as $H_o: \mathbf{\eta}=( \eta_1,\ldots,\eta_{K+1})^T=\mathbf{0}$, where $\eta_i$'s are log
arxiv