Results 81 to 90 of about 1,875,600 (283)

Addressing common inferential mistakes when failing to reject the null-hypothesis [version 2; peer review: 2 approved]

open access: yesF1000Research
Failure to reject a null-hypothesis may lead to erroneous conclusions regarding the absence of an association or inadequate statistical power. Because an estimate (and its variance) can never be exactly zero, traditional statistical tests cannot ...
Amand Schmidt
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Addressing common inferential mistakes when failing to reject the null-hypothesis [version 3; peer review: 2 approved]

open access: yesF1000Research
Failure to reject a null-hypothesis may lead to erroneous conclusions regarding the absence of an association or inadequate statistical power. Because an estimate (and its variance) can never be exactly zero, traditional statistical tests cannot ...
Amand Schmidt
doaj   +1 more source

Understanding Statistical Testing

open access: yesSAGE Open, 2015
Statistical hypothesis testing is common in research, but a conventional understanding sometimes leads to mistaken application and misinterpretation.
Peter J. Veazie
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Statistical inference and statistical learning in economic research – selected challenges

open access: yesEkonomista
This paper presents the main trends and the most important challenges related to the use of classical and modern statistical methods in economic research.
Krzysztof Jajuga   +2 more
doaj   +1 more source

A Pragmatic Approach to Statistical Testing and Estimation (PASTE)

open access: yesHealth Professions Education, 2018
The p-value has dominated research in education and related fields and a statistically non-significant p-value is quite commonly interpreted as ‘confirming’ the null hypothesis (H0) of ‘equivalence’.
Jimmie Leppink
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy