Results 101 to 110 of about 3,450,267 (350)

A Statistic for Testing the Null Hypothesis of Elliptical Symmetry

open access: yesJournal of Multivariate Analysis, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Francisco J. Pérez   +2 more
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

A novel methodological framework for testing automated vehicle functions

open access: yesEuropean Transport Research Review, 2020
Since there are more and more highly automated vehicles in road transportation with various extremely safety-critical functions, it is crucial to intensify the development of testing methods.
Árpád Török
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

RETROSPECTIVE ANALYSIS IN HYPOTHESIS TESTING TO EVALUATE INDONESIA'S GINI RATIO AFTER COVID-19 PANDEMIC

open access: yesBarekeng
The study highlighted three essential roles of retrospective analysis in hypothesis testing, particularly as a priori analysis, post hoc analysis, and sensitivity analysis.
Karunia Eka Lestari   +4 more
doaj   +1 more source

Turning the Hands of Time Again: A Purely Confirmatory Replication Study and a Bayesian Analysis

open access: yesFrontiers in Psychology, 2015
In a series of four experiments, Topolinski and Sparenberg (2012; TS) found support for the conjecture that clockwise movements induce psychological states of temporal progression and an orientation toward the future and novelty.
Eric-Jan eWagenmakers   +12 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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