Results 61 to 70 of about 618,680 (239)

Statistical inference and statistical learning in economic research – selected challenges

open access: yesEkonomista
This paper presents the main trends and the most important challenges related to the use of classical and modern statistical methods in economic research.
Krzysztof Jajuga   +2 more
doaj   +1 more source

Understanding Statistical Testing

open access: yesSAGE Open, 2015
Statistical hypothesis testing is common in research, but a conventional understanding sometimes leads to mistaken application and misinterpretation.
Peter J. Veazie
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

A Pragmatic Approach to Statistical Testing and Estimation (PASTE)

open access: yesHealth Professions Education, 2018
The p-value has dominated research in education and related fields and a statistically non-significant p-value is quite commonly interpreted as ‘confirming’ the null hypothesis (H0) of ‘equivalence’.
Jimmie Leppink
doaj   +1 more source

Statistical significance and statistical power in hypothesis testing [PDF]

open access: yesJournal of Orthopaedic Research, 1990
AbstractExperimental design requires estimation of the sample size required to produce a meaningful conclusion. Often, experimental results are performed with sample sizes which are inappropriate to adequately support the conclusions made. In this paper, two factors which are involved in sample size estimation are detailed—namely type I (α) and type II
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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