Results 91 to 100 of about 59,568 (301)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
International Journal of Antennas and Propagation, 2022 In collectively perceiving an electromagnetic environment, the discrete or statistical method is used to characterize its characteristics. The information received by the sensor is not correlated with each other; therefore, there is no way to obtain the ...
Peiwei Gao, Yongfeng Zhi, Chufeng Hu
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
MathematicsLet (M,∇,g) be a statistical manifold and TM be its tangent bundle endowed with a twisted Sasaki metric G. This paper serves two primary objectives. The first objective is to investigate the curvature properties of the tangent bundle TM.
Lixu Yan +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Unsupervised learning of shape manifolds [PDF]
, 2007 Classical shape analysis methods use principal component analysis to reduce the dimensionality of shape spaces. The basic assumption behind these methods is that the subspace corresponding to the major modes of variation for a particular class of shapes ...
Bhalerao, Abhir +5 more
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The similarity between objects is a fundamental element of many learning algorithms. Most non-parametric methods take this similarity to be fixed, but much recent work has shown the advantages of learning it, in particular to exploit the local ...
Yoshua Bengio, Pascal Vincent
core
α-Connections and a Symmetric Cubic Form on a Riemannian Manifold
Entropy, 2017 In this paper, we study the construction of α -conformally equivalent statistical manifolds for a given symmetric cubic form on a Riemannian manifold.
Keiko Uohashi
doaj +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source