Results 71 to 80 of about 59,568 (301)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Conformally-projectively flat trans-Sasakian statistical manifolds
, 2019 In this study, the notion of trans-Sasakian statistical manifold is defined, some results for this manifold's curvature tensors are given, an example of 3-dimensional trans-Sasakian statistical manifold is constructed and some characterizations about ...
Kazan, Ahmet
core +1 more source
DiagnosticsBackground: Alzheimer’s disease is a progressive neurological condition marked by a decline in cognitive abilities. Early diagnosis is crucial but challenging due to overlapping symptoms among impairment stages, necessitating non-invasive, reliable ...
Ömer Akgüller +2 more
doaj +1 more source
Spectrum Sensing Method Based on Information Geometry and Deep Neural Network
Entropy, 2020 Due to the scarcity of radio spectrum resources and the growing demand, the use of spectrum sensing technology to improve the utilization of spectrum resources has become a hot research topic.
Kaixuan Du +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Manifold aligned density estimation [PDF]
, 2010 With the advent of the information technology, the amount of data we are facing today is growing in both the scale and the dimensionality dramatically. It thus raises new challenges for some traditional machine learning tasks.
Wang, Xiaoxia
core
A q-exponential statistical Banach manifold
, 2015 Letµbe a given probability measure andMµ the set ofµ-equivalent strictly positive probability densities -- In this paper we construct a Banach manifold on Mµ, modeled on the space L∞(p · µ) where p is a reference density, for the non-parametric q ...
Loaiza Ossa, Gabriel Ignacio +1 more
core +1 more source
Semiparametric estimation of shifts on compact Lie groups for image registration [PDF]
, 2008 In this paper we focus on estimating the deformations that may exist between similar images in the presence of additive noise when a reference template is unknown. The deformations aremodeled as parameters lying in a finite dimensional compact Lie group.
Vimond, Myriam +2 more
core +1 more source
Combinatorial Optimization with Information Geometry: The Newton Method
Entropy, 2014 e discuss the use of the Newton method in the computation of max(p → Εp [f]), where p belongs to a statistical exponential family on a finite state space.
Luigi Malagò, Giovanni Pistone
doaj +1 more source