Results 51 to 60 of about 2,833,548 (240)
DiagnosticsBackground: Alzheimer’s disease is a progressive neurological condition marked by a decline in cognitive abilities. Early diagnosis is crucial but challenging due to overlapping symptoms among impairment stages, necessitating non-invasive, reliable ...
Ömer Akgüller +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
On the orientability of the asset equilibrium manifold [PDF]
This paper addresses partly an open question raised in the Handbook of Mathematical Economics about the orientability of the pseudo-equilibrium manifold in the basic two-period General Equilibrium with Incomplete markets (GEI) model. For a broad class of
Philippe Bich
core +2 more sources
The sculpture Manifold: a band from a surface, a surface from a band [PDF]
, 2008 The steel sculpture Manifold consists of an 8 cm wide closed band of stainless steel that winds around in an intricate way, curving and coming very close to itself.
Osinga, HM +2 more
core
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Manifold signal processing for MIMO communications [PDF]
, 2009 textThe coding and feedback inaccuracies of the channel state information (CSI) in limited feedback multiple-input multiple-output (MIMO) wireless systems can severely impact the achievable data rate and reliability. The CSI is mathematically represented
Inoue, Takao, doctor of electrical and computer engineering
core
Pseudo-manifold geometries with applications [PDF]
, 2006 A Smarandache geometry is a geometry which has at least one Smarandachely denied axiom(1969), i.e., an axiom behaves in at least two different ways within the same space, i.e., validated and invalided, or only invalided but in multiple distinct ways and ...
Mao, Linfan, Linfan Mao
core +1 more source