Results 61 to 70 of about 59,568 (301)

SYMPLECTIC STRUCTURES ON STATISTICAL MANIFOLDS [PDF]

open access: yesJournal of the Australian Mathematical Society, 2011
AbstractA relationship between symplectic geometry and information geometry is studied. The square of a dually flat space admits a natural symplectic structure that is the pullback of the canonical symplectic structure on the cotangent bundle of the dually flat space via the canonical divergence. With respect to the symplectic structure, there exists a
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Investigating Statistical Submersions and Their Properties

open access: yesMathematics
This research aims to prove a sharp relationship between statistical submersions and doubly minimal immersions. We consider a non-trivial statistical submersion on a statistical manifold with isometric fibers.
Aliya Naaz Siddiqui, Fatimah Alghamdi
doaj   +1 more source

Deformed Algebras and Generalizations of Independence on Deformed Exponential Families

open access: yesEntropy, 2015
A deformed exponential family is a generalization of exponential families. Since the useful classes of power law tailed distributions are described by the deformed exponential families, they are important objects in the theory of complex systems.
Hiroshi Matsuzoe, Tatsuaki Wada
doaj   +1 more source

Information Geometry of the Exponential Family of Distributions with Progressive Type-II Censoring

open access: yesEntropy, 2021
In geometry and topology, a family of probability distributions can be analyzed as the points on a manifold, known as statistical manifold, with intrinsic coordinates corresponding to the parameters of the distribution. Consider the exponential family of
Fode Zhang   +2 more
doaj   +1 more source

Robustness of statistical manifolds

open access: yesTopology and its Applications, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Loi, A., Matta, S.
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Tensor Balancing on Statistical Manifold

open access: yesCoRR, 2017
We solve tensor balancing, rescaling an Nth order nonnegative tensor by multiplying N tensors of order N - 1 so that every fiber sums to one. This generalizes a fundamental process of matrix balancing used to compare matrices in a wide range of applications from biology to economics.
Mahito Sugiyama   +2 more
openaire   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy