Results 51 to 60 of about 53,985 (263)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Riemannian Holonomy Groups of Statistical Manifolds [PDF]

, 2014
Normal distribution manifolds play essential roles in the theory of information geometry, so do holonomy groups in classification of Riemannian manifolds.
Jiu, Lin, Li, Didong, Sun, Huafei, Tao, Chen   +3 more
core  

Statistical Mechanics of Self-Avoiding Manifolds (Part II)

, 2004
We consider a model of a D-dimensional tethered manifold interacting by excluded volume in R^d with a single point. Use of intrinsic distance geometry provides a rigorous definition of the analytic continuation of the perturbative expansion for arbitrary
Duplantier, Bertrand
core   +1 more source

Homogeneous statistical manifolds

Information Geometry
The methods of Information geometry have been glowing up to develop various subjects of theoretical physics, including quantum information systems. The present article has two purposes. The first one is to develop general theory of homogeneous statistical manifolds.
Inoguchi, Jun-ichi, Ohno, Yu
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Black-Box Optimization Using Geodesics in Statistical Manifolds

Entropy, 2015
Information geometric optimization (IGO) is a general framework for stochastic optimization problems aiming at limiting the influence of arbitrary parametrization choices: the initial problem is transformed into the optimization of a smooth function on a
Jérémy Bensadon
doaj   +1 more source

The Effect Of Microscopic Correlations On The Information Geometric Complexity Of Gaussian Statistical Models

, 2010
We present an analytical computation of the asymptotic temporal behavior of the information geometric complexity (IGC) of finite-dimensional Gaussian statistical manifolds in the presence of microcorrelations (correlations between microvariables).
Amari, Benenti, C. Cafaro, Cafaro, Cafaro, Cafaro, Cafaro, Cafaro, Casetti, Caticha, Caticha, Caticha, Caticha, D.-H. Kim, De Felice, Di Bari, Gell-Mann, Hartnett, Jacobi, Jaynes, Kawabe, Kawabe, Lebowitz, Lebowitz, Lebowitz, Prosen, Rozanov, S. Mancini, S.A. Ali, Shibata, Toffoli, Tribus   +31 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Implications and Consequences of SL(2R) as Invariance Group in the Description of Complex Systems Dynamics from a Multifractal Perspective of Motion

Entropy, 2022
Possible implications and consequences of using SL(2R) as invariance groups in the description at any scale resolution of the dynamics of any complex system are analyzed.
Lucian Dobreci, Oana Rusu, Decebal Vasincu, Mihaela Jarcău, Cristina Marcela Rusu, Silviu Gurlui, Vlad Ghizdovat, Alina Gavrilut, Maricel Agop   +8 more
doaj   +1 more source

Statistical Lorentzian geometry and the closeness of Lorentzian manifolds

, 2000
I introduce a family of closeness functions between causal Lorentzian geometries of finite volume and arbitrary underlying topology. When points are randomly scattered in a Lorentzian manifold, with uniform density according to the volume element, some ...
Ashtekar, Baez, Bel, Bombelli, Bombelli, Brightwell, Brown, Crane, De Pietri, Detweiler, Garriga, Gibbs, Gupta, Gupta, Hawking, Hawking, Iwasaki, Kempf, Kleitman, Luca Bombelli, Malament, Markopoulou, Moore, Overduin, Reisenberger, Rovelli, Seriu, Seriu, Seriu, Smolin, Sorkin, Szabados, Wesson, Wheeler, Wootters, Zalaletdinov   +35 more
core   +3 more sources