Results 61 to 70 of about 2,851,799 (287)

Chen Inequalities for Statistical Submanifolds of Kähler-Like Statistical Manifolds [PDF]

, 2019
We consider Kähler-like statistical manifolds, whose curvature tensor field satisfies a natural condition. For their statistical submanifolds, we prove a Chen first inequality and a Chen inequality for the invariant δ ( 2 , 2 )
Mayuko Kon, Kazuhiko Takano, Kon, Mayuko, Mihai, Adela, Takano, Kazuhiko, Özgür, Cihan, Cihan Özgür, Aytimur, Hülya, Hülya Aytimur, Adela Mihai   +9 more
core   +1 more source

Hypersurfaces in statistical manifolds

Differential Geometry and its Applications, 2009
A statistical structure on a manifold \(M\) consists of a Riemannian metric \(g\) and a torsion-free affine connection \(\nabla\) that satisfies \( (\nabla_Xg)(Y,Z) = (\nabla_Yg)(X,Z)\) for all vector fields \(X\), \(Y\), and \(Z\) on \(M\). The statistical manifold \((M, \nabla, g)\) has constant curvature \(k\) if \[ R^\nabla(X,Y)Z = k(g(Y,Z)X-g(X,Z ...
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

An Alzheimer’s disease category progression sub-grouping analysis using manifold learning on ADNI

Scientific Reports, 2023
Many current statistical and machine learning methods have been used to explore Alzheimer’s disease (AD) and its associated patterns that contribute to the disease.
Dustin van der Haar, Ahmed Moustafa, Samuel L. Warren, Hany Alashwal, Terence van Zyl   +4 more
doaj   +1 more source

SYMPLECTIC STRUCTURES ON STATISTICAL MANIFOLDS [PDF]

Journal of the Australian Mathematical Society, 2011
AbstractA relationship between symplectic geometry and information geometry is studied. The square of a dually flat space admits a natural symplectic structure that is the pullback of the canonical symplectic structure on the cotangent bundle of the dually flat space via the canonical divergence. With respect to the symplectic structure, there exists a
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Solitonic aspects of submanifolds in Kenmotsu statistical manifolds [PDF]

, 2023
The differential geometry of Kenmotsu manifold is a valuable part of contact geometry with nice applications in other fields such as theoretical physics.
Siddiqui, Aliya Naaz, Siddiqi, Mohd. Danish   +1 more
core  

Statistical exploration of the manifold hypothesis

Journal of the Royal Statistical Society Series B: Statistical Methodology
Abstract The manifold hypothesis is a widely accepted tenet of machine learning which asserts that nominally high-dimensional data are in fact concentrated near a low-dimensional manifold, embedded in high-dimensional space. This phenomenon is observed empirically in many real-world situations, has led to development of a wide range ...
Nick Whiteley, Annie Gray, Patrick Rubin-Delanchy   +2 more
openaire   +3 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source