Results 81 to 90 of about 2,851,799 (287)
Geodesic Monte Carlo on Embedded Manifolds [PDF]
, 2013 Markov chain Monte Carlo methods explicitly defined on the manifold of probability distributions have recently been established. These methods are constructed from diffusions across the manifold and the solution of the equations describing geodesic flows
Simon Byrne +5 more
core +1 more source
Solution manifold and its statistical applications
Electronic Journal of Statistics, 2022 Accepted to the Electronic Journal of Statistics.
openaire +4 more sources
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Quasi-Kahler Chern-flat manifolds and complex 2-step nilpotent Lie algebras [PDF]
, 2012 The study of quasi-Kaehler Chern-flat almost Hermitian manifolds is strictly related to the study of anti-bi-invariant almost complex Lie algebras.
Lauret, J. +2 more
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Kahler manifolds and their relatives [PDF]
, 2010 Let M1 and M2 be two K¨ahler manifolds. We call M1 and M2 relatives if they share a non-trivial K¨ahler submanifold S, namely, if there exist two holomorphic and isometric immersions (K¨ahler immersions) h1 : S → M1 and h2 : S → M2. Moreover, two K¨ahler
Loi, A., Di Scala, Antonio Jose'
core
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Entropy, 2017 Information geometry enables a deeper understanding of the methods of statistical inference. In this paper, the problem of nonlinear parameter estimation is considered from a geometric viewpoint using a natural gradient descent on statistical manifolds ...
Yongqiang Cheng, Xuezhi Wang, Bill Moran
doaj +1 more source
Geometry of chen invariants in statistical warped product manifolds
, 2020 In this paper, we derive Chen inequality for statistical submanifold of statistical warped product manifolds R x (f) M. Further, we derive Chen inequality for Legendrian statistical submanifold in statistical warped product manifolds R x (f) M.
Chen, Bang-Yen +4 more
core +1 more source