Results 91 to 100 of about 2,732,414 (284)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
A survey on information geometry: statistical manifolds and statistical models
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y NaturalesThis survey presents an exposition of the foundational concepts of information geometry from a probabilistic viewpoint, as well as recent developments in differential geometry related to this área of information science.
Nicolás Martínez-Alba +1 more
doaj +1 more source
Entropy, 2017 Information geometry enables a deeper understanding of the methods of statistical inference. In this paper, the problem of nonlinear parameter estimation is considered from a geometric viewpoint using a natural gradient descent on statistical manifolds ...
Yongqiang Cheng, Xuezhi Wang, Bill Moran
doaj +1 more source
Asymmetric Topologies on Statistical Manifolds [PDF]
, 2015 8 pages, in Proceedings of the Second International Conference, GSI 2015, Palaiseau, France, October 28-30 ...
openaire +4 more sources
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
A General Type of Almost Contact Manifolds [PDF]
Among almost contact manifolds Sasakian manifolds, Kenmotsu manifolds (called also “a certain class of almost contact manifolds”) and cosymplectic manifolds have been studied by many authors.
Catalin Angelo Ioan
core
Vector bundles on manifolds: the cohomology of projective algebraic varieties [PDF]
, 2004 This Thesis looks at different areas of mathematics which require the notion of a differentiable manifold. The first three chapters contain various materials such as differentiable manifolds, submanifolds, tangent bundles, differential forms ...
Al-Ofi, Abdulaziz Slaim
core
Investigating Statistical Submersions and Their Properties
MathematicsThis research aims to prove a sharp relationship between statistical submersions and doubly minimal immersions. We consider a non-trivial statistical submersion on a statistical manifold with isometric fibers.
Aliya Naaz Siddiqui, Fatimah Alghamdi
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Subgroup separability, knot groups, and graph manifolds
, 2000 This paper answers a question of Burns, Karrass and Solitar by giving examples of knot and link groups which are not subgroup-separable. For instance, it is shown that the fundamental group of the square knot complement is not subgroup separable.
Wise, Daniel T. +3 more
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