Results 71 to 80 of about 468,748 (305)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Extremal Matching Energy of Random Polyomino Chains

open access: yesEntropy, 2017
Polyomino graphs is one of the research objectives in statistical physics and in modeling problems of surface chemistry. A random polyomino chain is a subgraph of a polyomino graph.
Tingzeng Wu, Huazhong Lü, Xuexin Zhang
doaj   +1 more source

Suffix sorting via matching statistics

open access: yesAlgorithms for Molecular Biology
AbstractWe introduce a new algorithm for constructing the generalized suffix array of a collection of highly similar strings. As a first step, we construct a compressed representation of the matching statistics of the collection with respect to a reference string.
Zsuzsanna Lipták   +2 more
openaire   +8 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Spatially-constrained Keypoint Matching for Efficient Statistical Shape Modelling

open access: yesCurrent Directions in Biomedical Engineering
Statistical shape models (SSMs) allow the compact description of the variability of object shapes within a given sample set. They are commonly used in medical imaging to model and analyse the shape of anatomical structures such as organs.
Harkämper Lena   +2 more
doaj   +1 more source

Data Integration: Techniques and Evaluation

open access: yesAustrian Journal of Statistics, 2016
Within the DIECOFIS framework, ec3, the Division of Business Statistics from the Vienna University of Economics and Business Administration and ISTAT worked together to find methods to create a comprehensive database of enterprise data required for ...
Michaela Denk, Peter Hackl
doaj   +1 more source

"Statistical Matching Using Propensity Scores: Theory and Application to the Levy Institute Measure of Economic Wellbeing" [PDF]

open access: yes
This paper summarizes the background, type, logic, and working procedure of the statistical matching used in the Levy Institute Measure of Economic Wellbeing (LIMEW) project to combine the various data sets used to produce the synthetic data set with ...
Hyunsub Kum, Thomas Masterson
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

An R-Shiny Application for Statistical Matching

open access: yes
Statistical matching involves integrating different data sources with different units and a set of common variables. Applying statistical matching methods presents challenges for practitioners, including data pre-processing and the application of ...
Trivisano, Carlo   +2 more
core   +1 more source

Statistical Matching: Hotdeck or Propensity Score?

open access: yes, 2023
This empirical study compares hotdeck and propensity score statistical matching (SM) procedures with the aim of providing useful guidance to researchers interested in the implementation of SM methods.
Elena Dalla Chiara   +2 more
core  

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