Results 111 to 120 of about 3,502,217 (294)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
introduction to the special jmp issue: statistical mechanics on random structures
, 2008 Introduzione al numero speciale di JMP "statistical mechanics on random ...
cristian Giardina, CONTUCCI, PIERLUIGI
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Planck's formula and glassy behavior in classical nonequilibrium statistical mechanics
, 2000 In statistical mechanics it is well known that one has to take into account the role of the relaxation times to equilibrium. We discuss the relevance of this fact for systems of weakly coupled harmonic oscillators in a classical framework, showing how ...
L. Galgani, A. Carati
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Heat-exchange statistics in driven open quantum systems
New Journal of Physics, 2014 As the dimensions of physical systems approach the nanoscale, the laws of thermodynamics must be reconsidered due to the increased importance of fluctuations and quantum effects.
S Gasparinetti +3 more
doaj +1 more source
Covariant statistical mechanics
Il Nuovo Cimento B Series 10, 1968 1. The relativistic t ransformation properties of thermodynamical quantities have been discussed even before the advent of the special theory of relativity. In 1904 HASENOEHRL (1) derived a formula for the spectral intensi ty of the radiation emit ted from a moving black body. By 1919 the problem seemed to be solved and clearly understood: a chapter in
openaire +2 more sources
Inferential vs. Dynamical Conceptions of Physics [PDF]
, 2013 I contrast two possible attitudes towards a given branch of physics: as inferential (i.e., as concerned with an agent's ability to make predictions given finite information), and as dynamical (i.e., as concerned with the dynamical equations governing ...
Wallace, David, David Wallace
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A statistical mechanics approach to autopoietic immune networks
, 2010 In this work we aim to bridge theoretical immunology and disordered statistical mechanics. We introduce a model for the behavior of B-cells which naturally merges the clonal selection theory and the autopoietic network theory as a whole.
Adriano Barra +4 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Brussels-Austin Nonequilibrium Statistical Mechanics in the Later Years: Large Poincaré Systems and Rigged Hilbert Space [PDF]
, 2003 This second part of a two-part essay discusses recent developments in the Brussels-Austin Group after the mid 1980s. The fundamental concerns are the same as in their similarity transformation approach (see Part I), but the contemporary approach utilizes
Bishop, Robert
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