Results 131 to 140 of about 3,502,217 (294)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Statistical Mechanics I: Statistical Mechanics of Particles

open access: yes, 2005
Statistical Mechanics is a probabilistic approach to equilibrium properties of large numbers of degrees of freedom. In this two-semester course, basic principles are examined.
Kardar, Mehran
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Statistical mechanics of dynamical system identification

open access: yesPhysical Review Research
Recovering dynamical equations from observed noisy data is the central challenge of system identification. We develop a statistical mechanics approach to analyze sparse equation discovery algorithms, which typically balance data fit and parsimony via ...
Andrei A. Klishin   +3 more
doaj   +1 more source

The statistical mechanics of Hawking radiation

open access: yesPhysics Letters B
Hawking radiation and black hole thermodynamics are well understood in the frameworks of quantum field theory and general relativity, with contemporary extensions in string theory, AdS/CFT, and loop quantum gravity. However, an open question remains: Can
Noah M. MacKay
doaj   +1 more source

Statistical Mechanics I: Statistical Mechanics of Particles

open access: yes, 2007
Statistical Mechanics is a probabilistic approach to equilibrium properties of large numbers of degrees of freedom. In this two-semester course, basic principles are examined.
Kardar, Mehran
core  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Can the jamming transition be described using equilibrium statistical mechanics?

open access: yes, 2011
When materials such as foams or emulsions are compressed, they display solid behaviour above the so-called 'jamming' transition. Because compression is done out of equilibrium in the absence of thermal fluctuations, jamming appears as a new kind of a ...
Zamponi F, Jacquin H, Berthier L
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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