Results 121 to 130 of about 690,585 (322)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Mesoscopic virial equation for nonequilibrium statistical mechanics

open access: yesNew Journal of Physics, 2016
We derive a class of mesoscopic virial equations governing energy partition between conjugate position and momentum variables of individual degrees of freedom.
G Falasco, F Baldovin, K Kroy, M Baiesi
doaj   +1 more source

Linked-Diagram Expansions for Quantum Statistical Mechanics [PDF]

open access: green, 1959
A. E. Glassgold   +2 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Statistical mechanics of dynamical system identification

open access: yesPhysical Review Research
Recovering dynamical equations from observed noisy data is the central challenge of system identification. We develop a statistical mechanics approach to analyze sparse equation discovery algorithms, which typically balance data fit and parsimony via ...
Andrei A. Klishin   +3 more
doaj   +1 more source

The scientific way of thinking in statistics, statistical physics and quantum mechanics [PDF]

open access: yes
This paper focuses on the way of thinking in both classical and modern Physics and Statistics, Statistical Mechanics or Statistical Physics and Quantum Mechanics.
Săvoiu, Gheorghe
core   +1 more source

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