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Is statistical learning a mechanism? [PDF]
Philosophical Psychology, 2016 AbstractPhilosophers of science have offered several definitions of mechanism, most of which have biological or neuroscientific roots. In this paper, I consider whether these definitions apply equally well to cognitive science. I examine this question by looking at the case of statistical learning, which has been called a domain-general learning ...
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Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
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Thermodynamics and Statistical Mechanics of Small Systems
Entropy, 2018 A challenging frontier in modern statistical physics is concerned with systems with a small number of degrees of freedom, far from the thermodynamic limit.[...]
Andrea Puglisi +2 more
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Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
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Ergodic hypothesis in classical statistical mechanics
Revista Brasileira de Ensino de FísicaAn updated discussion on physical and mathematical aspects of the ergodic hypothesis in classical equilibrium statistical mechanics is presented. Then a practical attitude for the justification of the microcanonical ensemble is indicated.
César R. de Oliveira, Thiago Werlang
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Errata : On the Statistical Mechanics of Liquids, and the Gas of Hard Elastic Spheres [PDF]
, 1944 O. K. Rice
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Statistical mechanics of the neocortex
Progress in Biophysics and Molecular Biology, 2009 We analyze neocortical dynamics using field theoretic methods for non-equilibrium statistical processes. Assuming the dynamics is Markovian, we introduce a model that describes both neural fluctuations and responses to stimuli. We show that at low spiking rates, neocortical activity exhibits a dynamical phase transition which is in the universality ...
Michael A. Buice, Jack D. Cowan
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