Results 51 to 60 of about 5,428,123 (293)

Canonical Ensemble in Non-extensive Statistical Mechanics [PDF]

, 2015
The framework of non-extensive statistical mechanics, proposed by Tsallis, has been used to describe a variety of systems. The non-extensive statistical mechanics is usually introduced in a formal way, using the maximization of entropy. In this article we investigate the canonical ensemble in the non-extensive statistical mechanics using a more ...
arxiv   +1 more source

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, EarlyView.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

The statistical mechanics of networks

, 2004
We study the family of network models derived by requiring the expected properties of a graph ensemble to match a given set of measurements of a real-world network, while maximizing the entropy of the ensemble.
E. T. Jaynes, J. E. Besag, J. M. Kleinberg, Juyong Park, M. E. J. Newman, P. Erdős, P. Erdős, T. A. B. Snijders, W. T. Grandy, Jr.   +8 more
core   +1 more source

Statistical mechanics of bubbly liquids [PDF]

, 1996
The dynamics of bubbles at high Reynolds numbers is studied from the viewpoint of statistical mechanics. Individual bubbles are treated as dipoles in potential flow.
Brady, John F., Yurkovetsky, Yevgeny
core   +1 more source

Edwards Statistical Mechanics for Jammed Granular Matter [PDF]

, 2016
In 1989, Sir Sam Edwards made the visionary proposition to treat jammed granular materials using a volume ensemble of equiprobable jammed states in analogy to thermal equilibrium statistical mechanics, despite their inherent athermal features. Since then,
A. Baule, F. Morone, H. Herrmann, H. Makse   +3 more
semanticscholar   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

Molecular Oncology, EarlyView.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch, Sara Sánchez‐Serra, Marta Rosàs‐Lapeña, Nicolás Costa‐Fraga, Judit Besalú‐Velázquez, Janet Illa‐Bernadí, Silvia Mateo‐Lozano, Florencia Cidre‐Aranaz, Thomas G.P. Grünewald, Ángel Díaz‐Lagares, Roser Lopez‐Alemany, Òscar M. Tirado   +11 more
wiley   +1 more source

Heat and Entropy in nonextensive thermodynamics [PDF]

, 2003
The concepts of quantity of heat and work are deduced in the non-extensive statistical mechanics context, following steps in parallel to those employed in the extensive statistical mechanics.
arxiv   +1 more source

Statistical Mechanics of Structural Fluctuations

, 1997
The theory of mesoscopic fluctuations is applied to inhomogeneous solids consisting of chaotically distributed regions with different crystalline structure.
Battaglia, Beck, Bhattacharya, Binder, Bruce, Bruce, Clapp, Cotterill, Curran, Dobryakov, Feijoo, Frenkel, Gibaud, Gooding, Hidaka, Kadantseva, Khait, Khait, Kislinsky, Koga, Koga, Masden, Mashimo, Meissner, Moleko, Moleko, Ohmine, Ohnari, Peierls, Pines, Pushkarov, Rechav, Rousset, Runge, Saxena, Sciortino, Shumovsky, Sinitsin, Speedy, Stamenkovic, Ubbelohde, V.I. Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Zubov   +60 more
core   +1 more source