Results 71 to 80 of about 104,046 (256)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

STATISTICAL MECHANICS OF THE VACUUM [PDF]

open access: yesModern Physics Letters B, 2012
The vacuum is full of virtual particles which exist for short moments of time. In this paper, we construct a chaotic model of vacuum fluctuations associated with a fundamental entropic field that generates an arrow of time. The dynamics can be physically interpreted in terms of fluctuating virtual momenta. This model leads to a generalized statistical
openaire   +2 more sources

UNCERTAINTY RELATIONS OF STATISTICAL MECHANICS [PDF]

open access: yesModern Physics Letters B, 2009
Recently, we have presented some simple arguments supporting the existence of a certain complementarity between thermodynamic quantities of temperature and energy, an idea suggested by Bohr and Heinsenberg in the early days of Quantum Mechanics. Such a complementarity is expressed as the impossibility to perform an exact simultaneous determination of ...
Velazquez, Luisberis, Curilef, Sergio
openaire   +6 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Statistical Mechanics of Thin Spherical Shells

open access: yesPhysical Review X, 2017
We explore how thermal fluctuations affect the mechanics of thin amorphous spherical shells. In flat membranes with a shear modulus, thermal fluctuations increase the bending rigidity and reduce the in-plane elastic moduli in a scale-dependent fashion ...
Andrej Košmrlj, David R. Nelson
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

STATISTICAL MECHANICS OF ANYONS

open access: yesNuclear Physics B, 1985
We study the statistical mechanics of a two-dimensional gas of free anyons-particles which interpolate between Bose-Einstein and Fermi-Dirac character. Thermodynamic quantities are discussed in the low-density regime. In particular, the second virial coefficient is evaluated by two different methods and is found to exhibit a simple, periodic, but ...
Daniel P. Arovas   +3 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ideas by Statistical Mechanics (Ism) [PDF]

open access: yesSSRN Electronic Journal, 2006
Ideas by Statistical Mechanics (ISM) is a generic program to model evolution and propagation of ideas/patterns throughout populations subjected to endogenous and exogenous interactions. The program is based on the author's work in Statistical Mechanics of Neocortical Interactions (SMNI), and uses the author's Adaptive Simulated Annealing (ASA) code for
openaire   +3 more sources

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