Results 51 to 60 of about 132,756 (302)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Closed Trans-Scale Statistical Microdamage Mechanics [PDF]

open access: yes, 2002
Damage and failure due to distributed microcracks or microvoids are on the challenging frontiers of solid mechanics. This appeals strongly to tools not yet fully developed in continuum damage mechanics, in particular to irreversible statistical ...
李晖凌   +4 more
core  

Statistical mechanics for non-Hermitian quantum systems

open access: yesPhysical Review Research, 2023
We present a systematic study of statistical mechanics for non-Hermitian quantum systems. Our work reveals that the stability of a non-Hermitian system necessitates the existence of a single path-dependent conserved quantity, which, in conjunction with ...
Kui Cao, Su-Peng Kou
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

What is Statistical Mechanics? [PDF]

open access: yes, 2012
Thermodynamics describes a large class of phenomena we observe in macroscopic systems. The aim of statistical mechanics is to account for this behaviour in terms of the dynamical laws governing the microscopic constituents of macroscopic systems and ...
Frigg, Roman
core  

New trends in nonequilibrium statistical mechanics: classical and quantum systems

open access: yes, 2020
The main aim of this special issue is to report recent advances and new trends in nonequilibrium statistical mechanics of classical and quantum systems, from both theoretical and experimental points of view, within an interdisciplinary context.
Dubkov A. A., Valenti D., Spagnolo B.
core   +1 more source

Several identities in statistical mechanics

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1994
In an earlier paper concerning a solvable Inodel in statistical mechanics, Miwa and Jimbo state a theta-function identity which they have checked to the 200th power, but of which they do not have a proof.
M. D. Hirschhorn
doaj   +1 more source

Detailed Fluctuation Theorems: A Unifying Perspective

open access: yesEntropy, 2018
We present a general method to identify an arbitrary number of fluctuating quantities which satisfy a detailed fluctuation theorem for all times within the framework of time-inhomogeneous Markovian jump processes.
Riccardo Rao, Massimiliano Esposito
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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