Results 81 to 90 of about 132,756 (302)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Emergence and Interpretation of Probability in Bohmian Mechanics [PDF]
, 2007 A persistent question about the deBroglie–Bohm interpretation of quantum mechanics concerns the understanding of Born’s rule in the theory. Where do the quantum mechanical probabilities come from? How are they to be interpreted? These are the problems of
Callender, Craig
core
STATISTICAL MECHANICS AND CHEMISTRY. [PDF]
Journal of the American Chemical Society, 1921 n ...
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Introduction to lattice statistical mechanics [PDF]
, 2016 This book is an introduction to statistical mechanics suitable for readers knowing basic measure theory. The mathematical prerequisites are summarized in Chapter 1.
Saburov, Mansoor +2 more
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Thermodynamically consistent coarse graining of biocatalysts beyond Michaelis–Menten
New Journal of Physics, 2018 Starting from the detailed catalytic mechanism of a biocatalyst we provide a coarse-graining procedure which, by construction, is thermodynamically consistent.
Artur Wachtel +2 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Statistical mechanics of driven diffusive systems
, 1995 Far-from-equilibrium phenomena, while abundant in nature, are not nearly as well understood as their equilibrium counterparts. On the theoretical side, progress is slowed by the lack of a simple framework, such as the Boltzmann-Gbbs paradigm in the case ...
Schmittmann, B +5 more
core +1 more source
STATISTICAL MECHANICS OF THE VACUUM [PDF]
Modern Physics Letters B, 2012 The vacuum is full of virtual particles which exist for short moments of time. In this paper, we construct a chaotic model of vacuum fluctuations associated with a fundamental entropic field that generates an arrow of time. The dynamics can be physically interpreted in terms of fluctuating virtual momenta. This model leads to a generalized statistical
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source