Results 31 to 40 of about 5,544 (263)
On Determining Continuum Quantities of Non-Equilibrium Processes via Molecular Dynamics Simulations [PDF]
, 2013 In this dissertation, a high-fidelity atomistic-to-continuum link for highly non-equilibrium processes has been established by making several modifications to Hardy’s theory.
Fu, Yao
core
Full-field evaluation of the onset of microplasticity in a steel specimen [PDF]
, 2009 This work deals with the study of the local onset of microplasticity in a steel specimen under tensile test through the use of a full-field strain measurement method at the micrometric scale.
Moulart, Raphaël +2 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
, 2017 This chapter contains the essential statistical mechanics required to understand the inner workings of, and interpretation of results from, computer simulations.
Michael P. Allen, Dominic J. Tildesley
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
PLoS ONE, 2014 X-ray crystallography is the predominant method for obtaining atomic-scale information about biological macromolecules. Despite the success of the technique, obtaining well diffracting crystals still critically limits going from protein to structure. In practice, the crystallization process proceeds through knowledge-informed empiricism. Better physico-
Fusco, Diana +6 more
openaire +7 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Geometric variational problems of statistical mechanics and of combinatorics
, 2000 10 pagesWe present the geometric solutions of the various extremal problems of statistical mechanics and combinatorics. Together with the Wulff construction, which predicts the shape of the crystals, we discuss the construction which exhibits the shape ...
Shlosman, Senya, Senya Shlosman
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Measurement of the Rare Transition b→sγ Using the Complete BABAR Data Set [PDF]
, 2011 We present the results of a measurement of the total rate and photon energy spectrum in b -> sγ transitions using the entire BABAR data set, 429 fb-1.
Doll, David Andrew
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Identities for Correlation Functions in Classical Statistical Mechanics and the Problem of Crystal States [PDF]
Journal of Statistical Physics, 2020 Let $z$ be the activity of point particles described by classical equilibrium statistical mechanics in ${\bf R}^ν$. The correlation functions $ρ^z(x_1,\dots,x_k)$ denote the probability densities of finding $k$ particles at $x_1,\dots,x_k$. Letting $ϕ^z(x_1,\dots,x_k)$ be the cluster functions corresponding to the $ρ^z(x_1,\dots,x_k)/z^k$ we prove ...
openaire +3 more sources