Results 71 to 80 of about 15,642,380 (303)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Top 10 metrics for life science software good practices [version 1; referees: 2 approved]
F1000Research, 2016 Metrics for assessing adoption of good development practices are a useful way to ensure that software is sustainable, reusable and functional. Sustainability means that the software used today will be available - and continue to be improved and supported
Haydee Artaza +11 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Public health informatics specialists in state and local public health workforce: insights from public health workforce interests and needs survey [PDF]
Objective: Modernizing and strengthening the US public health data and information infrastructure requires a strong public health informatics (PHI) workforce.
Leider, Jonathon P. +5 more
core +1 more source
Digital Methodology to implement the ECOUTER engagement process [version 2; referees: 2 approved]
F1000Research, 2017 ECOUTER (Employing COnceptual schema for policy and Translation E in Research – French for ‘to listen’ – is a new stakeholder engagement method incorporating existing evidence to help participants draw upon their own knowledge of cognate issues and ...
Rebecca C. Wilson +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Health Sciences Library and Informatics Center Strategic Plan FY22-FY24
, 2022 This document is the UNM Health Sciences Library and Informatics Center\u27s strategic plan for FY2022 ...
Health Sciences Library and Informatics Center
core
Why sensitive bacteria are resistant to hospital infection control [version 2; referees: 2 approved]
Wellcome Open Research, 2017 Background: Large reductions in the incidence of antibiotic-resistant strains of Staphylococcus aureus and Clostridium difficile have been observed in response to multifaceted hospital-based interventions.
Esther van Kleef +3 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Digital methodology to implement the ECOUTER engagement process [version 1; referees: 2 approved]
F1000Research, 2016 ECOUTER (Employing COnceptUal schema for policy and Translation Engagement in Research) – French for ‘to listen’ – is a new stakeholder engagement method incorporating existing evidence to help participants draw upon their own knowledge of cognate issues
Rebecca C. Wilson +5 more
doaj +1 more source