Results 41 to 50 of about 3,475,136 (310)

Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene. [PDF]

PLoS ONE, 2009
With recent advances in understanding of the neuroscience of risk taking, attention is now turning to genetic factors that may contribute to individual heterogeneity in risk attitudes.
Brian E Roe, Michael R Tilley, Howard H Gu, David Q Beversdorf, Wolfgang Sadee, Timothy C Haab, Audrey C Papp   +6 more
doaj   +1 more source

Sex-driven modifiers of Alzheimer risk

Neurology, 2020
Objective To investigate sex differences in late-onset Alzheimer disease (AD) risks by means of multimodality brain biomarkers (β-amyloid load via 11C-Pittsburgh compound B [PiB] PET, neurodegeneration via 18F-fluorodeoxyglucose [FDG] PET and structural ...
Aneela Rahman, Eva Schelbaum, Katherine Hoffman, I. Díaz, H. Hristov, Randolph D. Andrews, Steven Jett, Hande Jackson, Andrea Lee, H. Sarva, Silky Pahlajani, D. Matthews, J. Dyke, M. D. de Leon, R. Isaacson, R. Brinton, Lisa Mosconi   +16 more
semanticscholar   +1 more source

Topological Performance Measures as Surrogates for Physical Flow Models for Risk and Vulnerability Analysis for Electric Power Systems

, 2013
Critical infrastructure systems must be both robust and resilient in order to ensure the functioning of society. To improve the performance of such systems, we often use risk and vulnerability analysis to find and address system weaknesses.
Guikema, Seth, Hassel, Henrik, Johansson, Jonas, LaRocca, Sarah   +3 more
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Most ankle sprain research is either false or clinically unimportant: A 30-year audit of randomized controlled trials

Journal of Sport and Health Science, 2021
Background: Lateral ankle sprain is the most common musculoskeletal injury. Although clinical research in this field is growing, there is a broader concern that clinical trial outcomes are often false and fail to translate into patient benefits. Methods:
Chris M. Bleakley, Mark Matthews, James M. Smoliga   +2 more
doaj   +1 more source

Predictive accuracy of novel risk factors and markers: A simulation study of the sensitivity of different performance measures for the Cox proportional hazards regression model

Statistical Methods in Medical Research, 2015
Predicting outcomes that occur over time is important in clinical, population health, and health services research. We compared changes in different measures of performance when a novel risk factor or marker was added to an existing Cox proportional ...
P. Austin, Michael J Pencinca, E. Steyerberg   +2 more
semanticscholar   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

Actuarial and various entropy measures for a new extended log Kumaraswamy model: Properties and applications

Alexandria Engineering Journal
This article introduces a novel extension of the log Kumaraswamy distribution, termed Marshall Olkin log Kumaraswamy (MOLkw). The mathematical and statistical characteristics of the suggested distribution are constructed, encompassing explicit ...
Naif Alotaibi
doaj   +1 more source

The Uncertain Mortality Intensity Framework: Pricing and Hedging Unit-Linked Life Insurance Contracts [PDF]

, 2010
We study the valuation and hedging of unit-linked life insurance contracts in a setting where mortality intensity is governed by a stochastic process. We focus on model risk arising from different specifications for the mortality intensity.
Li, Jing, Szimayer, Alexander
core   +2 more sources