Results 61 to 70 of about 2,740,785 (266)

Topological Performance Measures as Surrogates for Physical Flow Models for Risk and Vulnerability Analysis for Electric Power Systems

, 2013
Critical infrastructure systems must be both robust and resilient in order to ensure the functioning of society. To improve the performance of such systems, we often use risk and vulnerability analysis to find and address system weaknesses.
Guikema, Seth, Hassel, Henrik, Johansson, Jonas, LaRocca, Sarah   +3 more
core   +1 more source

A novel risk-based analysis for the production system under epistemic uncertainty [PDF]

, 2013
Risk analysis of production system, while the actual and appropriate data is not available, will cause wrong system parameters prediction and wrong decision making. In uncertainty condition, there are no appropriate measures for decision making.
Khalaj, Amineh, Khalaj, Fereshteh, Khalaj, Mehran   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Mindfulness based interventions in multiple sclerosis: a systematic review [PDF]

, 2014
<b>Background</b> Multiple sclerosis (MS) is a stressful condition; depression, anxiety, pain and fatigue are all common problems. Mindfulness based interventions (MBIs) mitigate stress and prevent relapse in depression and are increasingly ...
A Damasceno, A Scalfari, AJ Dallmeijer, BK Hölzel, C McGuigan, CA Young, CH Polman, D Reviews UoYCf, DA Trojan, DC Mohr, DC Mohr, FP Robinson, Frances Mair, G Klevan, J Kabat-Zinn, J Kabat-Zinn, J Kabat-Zinn, J Piet, J Tavee, JD Teasdale, JH Kang, JJ Miller, Jo Booth, JP Higgins, KG Kahl, L Dennison, LA Chwastiak, LE Carlson, M Lawrence, Maggie Lawrence, N Mills, N Mills, ND Chiaravalloti, P Boland, P Grossman, P McCrone, P Thomas, R Marrie, R Marrie, RJ Davidson, RJM Franklin, Robert Simpson, S Kern, SA Warren, Sharon Byrne, Stewart Mercer, WI McDonald, WS Richardson, Y Bol   +48 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A New Method for Protecting Interrelated Time Series with Bayesian Prior Distributions and Synthetic Data [PDF]

, 2013
Organizations disseminate statistical summaries of administrative data via the Web for unrestricted public use. They balance the trade-off between confidentiality protection and inference quality.
Abowd, John M, Schneider, Matthew J
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Statistical approaches used to assess the equity of access to food outlets: a systematic review

, 2015
: Background Inequalities in eating behaviours are often linked to the types of food retailers accessible in neighbourhood environments. Numerous studies have aimed to identify if access to healthy and unhealthy food retailers is socioeconomically ...
Ester Cerin, Karen E. Lamb, Kylie Ball, Lukar E. Thornton, null null   +4 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Safety analysis of welding process in Tehran oil refinery and the effectiveness of the control methods

بهداشت و ایمنی کار, 2012
The safety of high risk jobs especially in oil refining activities is a major concern. In the present paper, the welding risks in Tehran oil refinery have been assessed using the Job Safety Analysis (JSA) and the effectiveness of the controlling methods ...
, , ,
doaj