Results 71 to 80 of about 2,204,741 (325)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Natural Hazards, 2016 Tsunami fragility curves are statistical models which form a key component of tsunami risk models, as they provide a probabilistic link between a tsunami intensity measure (TIM) and building damage. Existing studies apply different TIMs (e.g.
J. Macabuag +8 more
semanticscholar +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
بهداشت و ایمنی کار, 2012 The safety of high risk jobs especially in oil refining activities is a major concern. In the present paper, the welding risks in Tehran oil refinery have been assessed using the Job Safety Analysis (JSA) and the effectiveness of the controlling methods ...
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doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Protection of micro-data subject to edit constraints against statistical disclosure
, 2006 Before releasing statistical outputs, data suppliers have to assess if the privacy of the statistical units is endangered and apply Statistical Disclosure Control (SDC) methods if necessary. SDC methods perturb, modify or summarize the data, depending on
Shlomo, Natalie, de Waal, Ton
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Estimating risks of identification disclosure in partially synthetic data
, 2008 To limit disclosures, statistical agencies and other data disseminators can release partially synthetic, public use microdata sets. These comprise the units originally surveyed, but some collected values, for example sensitive values at high risk of ...
Reiter, Jerome P. +3 more
core +1 more source
A note on the statistical robustness of risk measures [PDF]
, 2017 The question of robustness in risk measurement emerged only fairly recently, but it hasalready attracted considerable attention. The problem has been studied using variousapproaches, and several methods aiming at robustifying the risk measures have ...
Valérie Chavez-Demoulin +5 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source