Results 131 to 140 of about 3,742,195 (269)

The pangenome: a statistical model, not a fixed biological property. [PDF]

Bioinform Adv
Guerra A.
europepmc   +1 more source

Quantifying Frailty Requires a Conceptual Model Before a Statistical Model. [PDF]

JAMA Surg, 2022
Reitz KM, Arya S, Hall DE.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Statistical model for factors correlating with COVID-19 deaths. [PDF]

Int J Disaster Risk Reduct, 2022
Nuutinen M, Haavisto I, Niemi AJ, Rissanen A, Ikivuo M, Leskelä RL.   +5 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

A statistical model for forecasting probabilistic epidemic bands for dengue cases in Brazil. [PDF]

Infect Dis Model
Picinini Freitas L, da Cruz Ferreira DA, Lana RM, Câmara DCP, Portella TP, Carvalho MS, Gouveia AS, de Almeida IF, Araujo EC, Vacaro LB, Ganem F, Cruz OG, Coelho FC, Codeço CT, Carvalho LM, Bastos LS.   +15 more
europepmc   +1 more source

Predicting Alcohol Consumption Patterns for Individuals with a User-Friendly Parsimonious Statistical Model. [PDF]

Int J Environ Res Public Health, 2023
Liang W, Chih H, Chikritzhs T.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

A Statistical Model to Estimate the Potential Risk of Work-Related Stroke among Office Workers: A Methodological Description Article. [PDF]

Iran J Public Health
Farghadan M, Almutairi NS, Shariat A, Anastasio AT.   +3 more
europepmc   +1 more source

Data analysis for COVID-19 deaths using a novel statistical model: Simulation and fuzzy application. [PDF]

PLoS One, 2023
El-Sherpieny EA, Almetwally EM, Muse AH, Hussam E.   +3 more
europepmc   +1 more source