Results 171 to 180 of about 33,140,363 (390)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A new statistical model for binge drinking pattern classification in college-student populations. [PDF]

Front Psychol, 2023
André J, Diouf M, Martinetti MP, Ortelli O, Gierski F, Fürst F, Pierrefiche O, Naassila M.   +7 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Predictive Statistical Model of Early Cranial Development. [PDF]

IEEE Trans Biomed Eng, 2022
PorrasPerez AR, Keating R, Lee J, Linguraru MG.   +3 more
europepmc   +1 more source

A Statistical Model for Indoor Multipath Propagation

IEEE J. Sel. Areas Commun., 1987
A. Saleh, R. Valenzuela
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A Bayesian approach to estimate the prevalence of low height-for-age from the prevalence of low weight-for-age

Cadernos de Saúde Pública
Victora et al. (1998) proposed the use of low weight-for-age prevalence to estimate the prevalence of height-for-age deficit in Brazilian children. This procedure was justified by the need to simplify methods used in the context of community health ...
Michael E. Reichenheim, Nicola G. Best
doaj  

Quantifying Frailty Requires a Conceptual Model Before a Statistical Model. [PDF]

JAMA Surg, 2022
Reitz KM, Arya S, Hall DE.
europepmc   +1 more source

Statistical modelling of spatio-temporal dependencies in NGS data [PDF]

, 2016
Saverio Ranciati
openalex   +1 more source

A Statistical Data Model [PDF]

, 1984
Bry, François, Havránek, Tomáš
core   +1 more source