Results 151 to 160 of about 2,290,848 (276)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Real-time prediction of soil bearing capacity in clayey soils using drilling parameters and statistical modeling. [PDF]

Sci Rep
Pande P, Giri J, Raut J, Sabeur H, Bhagat R, Azizi M.   +5 more
europepmc   +1 more source

Statistical modeling of multipath clusters in an office environment [PDF]

, 2012
Joseph, Wout, Martens, Luc, Tanghe, Emmeric   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Corrigendum to "Stable isotope and multi-elemental analysis combined with statistical modeling for saffron origin authentication" [Food Chem.: X 31 (2025) 103196]. [PDF]

Food Chem X
Terro C, Strojnik L, Potočnik D, Hudobivnik MJ, Mazej D, Bontempo L, Eddabdouby M, Amenzou NE, Moncef B, Kelly S, Ogrinc N.   +10 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A comparison of semi-parametric statistical modeling approaches to dynamic classification of irregularly and sparsely sampled curves. [PDF]

Stat Methods Med Res
Deneer R, Zhan Z, Van den Heuvel E, van Boxtel AG, Boer AK, van Riel NA, Scharnhorst V.   +6 more
europepmc   +1 more source

Editorial: Mathematical and statistical modeling of infection and transmission dynamics of viral diseases. [PDF]

Front Public Health, 2023
Oshinubi K, Magal P, Longe O, Demongeot J.   +3 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Tinnitus constancy and self-reported severe headache or migraine symptoms in peri- and postmenopausal women: a statistical modeling and machine learning analysis. [PDF]

Eur J Med Res
Jiang L, Cui Y, Du H.
europepmc   +1 more source