Results 141 to 150 of about 775,359 (318)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Refined mapping of ethnic minority population under the fusion of nighttime light data and multisource data

open access: yesScientific Reports
Understanding population distribution and ethnic composition is essential for formulating effective regional development plans, providing insights into the evolutionary characteristics of populations, unraveling historical human heritage, and fostering ...
Yiyang Zhang   +10 more
doaj   +1 more source

Contributions to statistical machine learning algorithm [PDF]

open access: yes, 2011
This thesis's research focus is on computational statistics along with DEAR (abbreviation of differential equation associated regression) model direction, and that in mind, the journal papers are written as contributions to statistical machine learning ...
Cui, Yan Hong
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Statistical Models of Ferrimagnetism [PDF]

open access: yesProgress of Theoretical Physics, 1955
Syozi, Itiro, Nakano, Huzio
openaire   +1 more source

Canonical foliations of statistical manifolds with statistical models

open access: yesInformation Geometry
Abstract Constructing a realisation of a statistical manifold as a statistical model, i.e a manifold with dual connections with respect to a Fisher metric, is an important question in information geometry. While a positive answer to this problem was given by the work on Hong Van Lé [1], writing explicitly the ...
Gnandi, Emmanuel   +2 more
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

On detecting and modeling periodic correlation in financial data [PDF]

open access: yes
For many economic problems standard statistical analysis, based on the notion of stationarity, is not adequate. These include modeling seasonal decisions of consumers, forecasting business cycles and - as we show in the present article - modeling ...
Rafal Weron   +3 more
core  

Can elearning platform use augment the statistical learning? Some evidence from Italy [PDF]

open access: yes, 2015
The study of statistics, in degree programs not specifically designed, is one of the most difficult obstacles to overcome in the students’ perspective.
Corrado Crocetta   +2 more
core  

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