Results 111 to 120 of about 6,283,547 (291)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Review of Data-Driven Approaches Applied to Time-Series Solar Irradiance Forecasting for Future Energy Networks

Energies
The fast-increasing penetration of photovoltaic (PV) power raises the issue of grid stability due to its intermittency and lack of inertia in power systems. Solar irradiance forecasting effectively supports advanced control, mitigates power intermittency,
Xuan Jiao, Weidong Xiao
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Method for a priori estimation of effective radial permeability to enhance the informativity of interpretative value of distorted pressure recovery curves in horizontally completed wells

Известия высших учебных заведений: Нефть и газ
Effective radial (horizontal) permeability is a crucial characteristic of a fluid-saturated reservoir. Understanding this parameter assists in addressing various scientific and practical challenges in the oil and gas industry.Effective radial ...
T. V. Kuzmina, A. G. Kozubovsky, S. K. Sokhoshko, M. Yu. Savastin   +3 more
doaj   +1 more source

Statistical Models for High Frequency Security Prices [PDF]

This article studies two extensions of the compound Poisson process with iid Gaussian innovations which are able to characterize important features of high frequency security prices.
Roel C.A. Oomen
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Fog, Friction, and Failure in Organized Conflict: A Formal Study

Axioms
Organized conflict, while confined by the laws of physics—and, under profound strategic incompetence, by the Lanchester equations—is not a physical process but rather an extended exchange between cognitive entities that have been shaped by path-dependent
Rodrick Wallace
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Statistical methods in grape and wine research for quantifying the impact of climate change

OENO One
Studies analysing the impact that climate change could have on the wine sector are important for determining appropriate adaptation strategies. Statistical methods provide a useful approach for estimating future climate impacts.
German Puga, Kym Anderson
doaj   +1 more source

Statistical skull models from 3D X-ray images

, 2006
We present 2 statistical models of the skull and mandible built upon an elastic registration method of 3D meshes. The aim of this work is to relate degrees of freedom of skull anatomy, as static relations are of main interest for anthropology and legal ...
Bailly, Gérard, Berar, Maxime, Desvignes, Michel, Payan, Yohan   +3 more
core   +1 more source